overdetection

overdetection

(ō″vĕr-dĕ-tek′shŏn)
The identification of clinically insignificant disease during screening programs designed to detect severe or malignant illnesses.
References in periodicals archive ?
Compared with the standard transrectal ultrasound-guided sextant biopsy, MRI-targeted biopsies detect more intermediate/high-risk cancer using fewer biopsy cores and reduce overdetection of low-risk cancer.
Two hypotheses attempt to explain this rapid increase: overdetection or a true increase of thyroid cancer.
In line with the definitions, a larger recall indicates less undetected anomaly (false negative), while a larger prevision indicates less overdetection (false positive).
(6-8) At present, philosophers of medicine, ethicists and health researchers are actively developing definitions of overdiagnosis and attempting to distinguish overdiagnosis from similar concepts such as overtreatment, overdetection, 'too much medicine' and medicalisation.
(3) Overdetection and subsequent overtreatment of indolent prostate cancer was estimated as > 50% in the European screening program.
However, evidence from existing research suggests that minor defects are not fully explained by overdetection (Tanner et al.
Lead times and overdetection due to prostate-specific antigen screening: Estimates from the European Randomized Study of Screening for Prostate Cancer.
There is some debate on whether this test should be performed in asymptomatic men because of associated overdetection or overtreatment of indolent disease.
"However, the Achilles' heel of PSA [prostate-specific antigen] testing is that it does so at the risk of overdetection --detecting disease that would not have become clinically apparent over a patient's lifetime if left untreated.
"We think that we've seen a leveling of overdetection, but I think we'll see another round of overdetection, because of a lowering PSA threshold to prompt biopsy; aggressive rescreening, the use of PSA velocity at low PSA values to prompt biopsy, and the use of saturation biopsies," he said during the conference, sponsored by the American Association for Cancer Research and the Prostate Cancer Foundation.
Thus 1 sequela of breast screening programs worldwide has been a marked increase in the overdetection and overtreatment of DCIS.
Lead times and overdetection due to PSA screening: estimates from the European Randomized Study of Screening for Prostate Cancer.