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The sudden increase in the incidence of a disease or condition.
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Patient discussion about outbreak

Q. Can Cholera outbreak here in the U.S? I looked for information about Cholera and couldn’t find much…

A. You can find any information in wikipedia. here is a link about Cholera :
and here is all the info about Cholera outbreaks in the world:

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References in classic literature ?
No less than one hundred and twenty rebellions are recorded in our annals, besides minor outbreaks numbered at two hundred and thirty-five; and they have all ended thus.
At the outbreak of the Revolution Burke was already sixty, and the inevitable tendency of his mind was away from the enthusiastic liberalism which had so strongly moved him in behalf of the Americans and the Hindoos.
As Mars approached opposition, Lavelle of Java set the wires of the astronomical exchange palpitating with the amazing intelli- gence of a huge outbreak of incandescent gas upon the planet.
The warning of a coming outbreak began to show itself in her face.
There are some bad nights in the kingdom of the West Wind for homeward-bound ships making for the Channel; and the days of wrath dawn upon them colourless and vague like the timid turning up of invisible lights upon the scene of a tyrannical and passionate outbreak, awful in the monotony of its method and the increasing strength of its violence.
M'Lellan, with his usual tranchant mode of dealing out justice, resolved to shoot the desperado on the spot in case of any outbreak. Nothing of the kind, however, occurred.
Towards the end of the term two or three boys caught scarlet fever, and there was much talk of sending them all home in order to escape an epidemic; but the sufferers were isolated, and since no more were attacked it was supposed that the outbreak was stopped.
Rosa, in her fright, made vain attempts to check this furious outbreak.
Daylight still engaged in daring speculations, as, for instance, at the impending outbreak of the Japanese-Russian War, when, in the face of the experience and power of the shipping gamblers, he reached out and clutched practically a monopoly of available steamer-charters.
The model estimated costs of 15 foodborne pathogens that caused outbreaks in restaurants from 2010 - 2015 as reported by the CDC.
Seven foodborne norovirus outbreaks were reported in remote areas across Japan during January-February 2017, causing illness in 2,094 persons (Figure).
Waterborne disease outbreaks in the United States are associated with a wide variety of water exposures and are reported annually to CDC on a voluntary basis by state and territorial health departments through the National Outbreak Reporting System (NORS).