ouabain


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oua·ba·in

(wah-bin, wah'bah-in),
A glycoside and African arrow poison from ouabaio, obtained from the wood of Acocanthera ouabaio or from the seeds of Strophanthus gratus; its action is qualitatively identical to that of strophanthus and the digitalis glycosides; used for rapid digitalization; often used in pharmacologic studies because of water solubility.
Farlex Partner Medical Dictionary © Farlex 2012

ouabain

(wä-bā′ĭn)
n.
A white poisonous glycoside, C29H44O12, extracted from the seeds of certain African trees of the genera Strophanthus and Acokanthera, that is used as a dart poison in some parts of Africa and has been used to treat congestive heart failure.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

ouabain

(wă-bā′ĭn)
A glycoside prepared from Strophanthus gratus. Its action is similar to that of digitalis.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
The (https://www.sciencedaily.com/releases/2018/01/180117164007.htm) American Chemical Society , which publishes the journal, explained that at low levels ouabain is used to regulate blood pressure or treat cardiac patients, but in higher doses can damage the heart.
OUA = ouabain ([Na.sup.+]/[K.sup.+]-ATPase inhibitor, 72.8 [micro]g/mL).
reported that ouabain, a compound in Acokanthera oppositifolia, can induce MDR expression in vitro.
They found the heart drug ouabain, when administered, can reduce the virus' replication.
Ouabain is a cardiac glycoside which specifically inhibits the [Na.sup.+], [K.sup.+]-ATPase (Mcllwain, 1963).
The a subunit is the catalytic unit and is responsible for binding of [Na.sup.+] and [K.sup.+] ions, ATP, and ouabain (an inhibitor).
Dubai: Ouabain and Baroque -- these are the words Rohan Kapur, 13 and Kavya Prasad,15 swear by these days.
The final assay concentrations of the chemicals used here were 135 mmol Tris-HCl (pH 7.4), 100 mmol NaCl, 10 ouabain, and 6 mmol ATP.
The animals' spiral ganglion neurons had been deliberately destroyed with a drug called ouabain, leaving them completely deaf.