ototoxic drug

ototoxic drug

ENT A drug that can damage the hearing and vestibular/balance organs of the inner ear
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The candidates with other known causes of hearing loss like ototoxic drug use, diabetes, those working in noisy environments like explosives, firearms, industrial machines, pneumatic drills, sirens, recurrent/ recent ear, nose complaints, those with history/ complaints of ear discharge were excluded from the study after screening via history taking and ENT examination.
The diagnosis of isolated PSCC-BPPV was made according to the Dix-Hallpike test, and subjects with the presence of spontaneous nystagmus and positive signs or symptoms regarding lateral or anterior canal BPPV, ototoxic drug use, blindness, neurological disorders, or poor neck range of motion were excluded from the study.
Four thousand eight hundred seventy-six (65%) of the babies were born by normal vaginal delivery and 2626 (35%) were born by cesarean section; 584 (7.8%) of these carried risk in terms of hearing loss: 62 patients had a familial history of congenital hearing loss, 17 patients were born with a birth weight of 1500 g and below, 124 patients had a history of hyperbilirubinemia, 351 patients had a history of ototoxic drug use, and 30 patients had a history of mechanical ventilation and ototoxic drug use for five days or more.
Ototoxicity refers to the hearing disorder that results from the temporary or permanent inner ear dysfunction after treatment with an ototoxic drug [10].
age related hearing loss, ototoxic drug use, certain infections like mumps etc.
Information was collected concerning the presence and timing of rash during pregnancy and on maternal or perinatal risk factors for congenital hearing loss, such as alcohol consumption, familial hearing loss, ototoxic drug exposure, birth trauma, and postnatal infections.
For the determination of hearing loss secondary to ototoxic drug use, PTA and DPOAE testing exhibit a good degree of consistency, and either can be used for the early detection of SNHL.
History of Ototoxic drug intake for a period of more than a month.
Reasons for exclusion were as follows: exposure to ototoxic substances (n = 6), head injury (n = 2), consumption of ototoxic drug (n = 1), head trauma (n = 1), and childhood infection (n = 1).
The remainder are either infectious (with congenital cytomegalovirus infection being the leading culprit), caused by maternal ototoxic drug use during pregnancy, or idiopathic.
The cases with a history of chronic infection, ear surgery, diabetes mellitus, renal failure, otolaryngology abnormalities (micro-vascular free flap reconstruction, lip-palate abnormalities), ototoxic drug use, acoustic and head traumas were eliminated from the study.