ototoxic


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ototoxic

 [o´to-tok″sik]
having a damaging effect upon the eighth cranial (vestibulocochlear) nerve or on the organs of hearing and balance.

o·to·tox·ic

(ō'tō-tok'sik),
Relating to ototoxicity.

ototoxic

/oto·tox·ic/ (o´to-tok″sik) having a deleterious effect upon the eighth nerve or on the organs of hearing and balance.

ototoxic

(ō′tə-tŏk′sĭk)
adj.
Having a toxic effect on the structures of the ear, especially on its nerve supply.

o′to·tox·ic′i·ty (-tŏk-sĭs′ĭ-tē) n.

ototoxic

adjective Referring to a substance or process that is toxic to the vestibulo-auditory apparatus.

o·to·tox·ic

(ō'tō-tok'sik)
Having a toxic action on the ear.
[oto- + G. toxikon, poison]

Ototoxic

Damaging to the nerves controlling the senses of hearing and balance.
Mentioned in: Tinnitus

ototoxic

having a deleterious effect upon the eighth cranial (vestibulocochlear) nerve or on the organs of hearing and balance.
References in periodicals archive ?
If the one infant with bilateral profound sensorineural hearing loss who had been treated with amikacin (a known ototoxic antibiotic) before the hearing testing is excluded, the proportion of infants with sensorineural hearing loss was 5.
Test frequencies associated with upper limits that are below 10 dB HL, indicated by the horizontal reference line, show sufficient evidence that interferon beta-1a is not ototoxic in relation to no DMT use at that audiometric test frequency.
Especially premature infants have the potential to be exposed to multiple risk factors including hyperbilirubinemia, use of mechanical ventilation, sepsis and use of ototoxic drugs and the frequency of hearing deficit increases as the frequency of morbidity including retinopathy of prematurity and chronic lung disease increases.
The remainder are either infectious (with congenital cytomegalovirus infection being the leading culprit), caused by maternal ototoxic drug use during pregnancy, or idiopathic.
The selected patients had no history of ear diseases or trauma, nor did they have ear surgery, abnormal ear examination, use ototoxic drugs and/or renal failure.
Aminoglycosides are known for their nephrotoxic and irreversible ototoxic effects.
It is inactivated by iodine, should not be used on mucous membranes, may cause chemical burns in neonates and is ototoxic (harmful to the ear) (Fletcher et al 2007, Milstone et al 2008, Sivathasan et al 2010).
Subsequent chapters address audiological monitoring for individuals exposed to ototoxic drugs; procedures for evaluation; current hearing protection and enhancement devices, regulations, procedures for selecting and fitting devices, and training workers in the use of devices; education and training; evaluating effectiveness of a program; procedures for musicians and treatment for music-induced hearing loss; conserving hearing in nonwork settings; worker's compensation; support and treatment for workers with hearing loss; hearing conservation in educational settings; and future trends like the use of antioxidants and gene therapy.
Individuals with any metabolic disorder, perforated eardrum, conductive deafness, history of use of ototoxic drugs, deafness of sudden onset and without their previous audiometric record were excluded from the study.
Common causes of sensorineural hearing loss include presbyacusis, chronic suppurative otitis media, Meniere's disease, ototoxic medications and noise exposure.