OS9(redirected from osteosarcoma amplified 9, endoplasmic reticulum lectin)
OS9A gene on chromosome 12q13 that encodes a ubiquitous lectin which binds selectively to improperly folded luminal proteins. OS9 plays a role in endoplasmic reticulum (ER) quality control and ER-associated degradation of misfolded proteins and retaining them in the ER, possibly transferring them to the ubiquitination machinery and promoting their degradation.
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