The presence of osteoprogenitor cells
and mesenchymal stem cells (MSCs), with the ability to differentiate into bone cells, is probably the predominant factor contributing to the increase in osteogenic activity and consequently, repair of bone injury.
Moreover, intermittent administration of hPTH1-34 stimulates the differentiation of osteoprogenitor cells
into osteoblasts [22, 23] and suppresses apoptosis in osteoblasts , thereby promoting bone formation.
The objective of this study was to investigate whether treatment with EM can diminish the inhibitory effects of PMMA particles on MC3T3-E1 osteoprogenitor cells
Increased bone formation by intermittent parathyroid hormone administration is due to the stimulation of proliferation and differentiation of osteoprogenitor cells
in bone marrow.
Expression of [beta]-catenin was concentrated in the osteoprogenitor cells
that line the trabecular regions (Figure 5C,D).
Ectopic ossification is believed to occur as the result of the transformation of primitive cells of a mesenchymal origin, which are present in the connective tissue septa, into osteoprogenitor cells
. (5) Chalmers et al proposed that three conditions are needed for this transformation to occur: the presence of inducing agents, osteogenic precursor cells, and a permissive environment.
Orthofix's Trinity product is an allograft of cancellous bone comprised of viable adult stem cells and osteoprogenitor cells
within the matrix and a demineralized bone component.
Effects of vitamin B12 on cell proliferation and cellular alkaline phosphatase activity in human bone marrow stromal osteoprogenitor cells
and UMR106 osteoblastic cells.
The histogenesis of ES remains controversial, and current wisdom as to the cellular origin is divided between mesenchymal cells, possibly osteoprogenitor cells
of the bone marrow, or neuroectodermal cells.
He found that an induction cell such as a histiocyte acts upon a connective tissue cell facilitating differentiation into the osteoprogenitor cells
. This bone inducing substance was referred to as bone morphogenetic protein (Lee, 1997).
They adorned the scaffolding with synthetic peptides, or protein fragments, that help bone-forming cells called osteoprogenitor cells
adhere to the framework.
Riccardi, "Differentiation of human osteoprogenitor cells
increases after treatment with pulsed electromagnetic fields," In Vivo (Brooklyn), vol.