(B) After 4 weeks of splinting, there is osteolysis
and osseous proliferation at the fracture site, consistent with a delayed union.
Our results showed that SR down-regulated the level of SOST, promoted bone formation, and inhibited osteolysis
, resulting in the inhibition of aseptic loosening in an aseptic loosening model of female mice.
"Perhaps even more intriguing is that the two biomarkers we identified also differed before surgery among patients who eventually developed peri-implant osteolysis
and those who did not, supporting the concept that other researchers have proposed of genetic risk factors for loosening."
B, Five-year postoperative radiograph showing no evidence of osteolysis
with progressive or persistent enhancement beyond 6 weeks is consistent with spondylodiscitis.
A postprocedure CT scan was performed to visualize polymethyl metacrylate (PMMA) distribution within the osteolysis
and local extraosseous cement leaks.
Goronzy, "The role of T lymphocytes in the periprosthetic inflammation of patients with total joint implant failure and osteolysis
," Journal of Investigative Medicine, vol.
is also seen mainly in the cortical bone (arrowheads).
Gorham-Stout syndrome (GSS), also known as Gorham's syndrome, idiopathic massive osteolysis
, disappearing bone, disease or phantom bone disease, is a rare skeletal disorder, characterized by osteolysis
of various bones accompanied by proliferative angiomatosis.
Choe, "Erosive arthropathy with osteolysis
as a typical feature in polyfibromatosis syndrome: a case report and a review of the literature," Journal of Korean Medical Science, vol.
Winchester syndrome is a rare inherited disease characterized by severe osteolysis
particularly in the hands and feet, generalized osteoporosis and absence of subcutaneous nodules.
In consideration for the relatively low effect and high adverse effect of second-line chemotherapy, in addition to the PD-L1 mutation revealed by gene sequencing, we decided to use zoledronic acids for maintenance of osteolysis
and anti-PD-1 monoclonal antibody to ensure the quality of life.