Second, this model only evaluated initial fixation and does not simulate the impact of any osseous integration; it is unknown whether implant osteointegration
in the clinical situation may mitigate early fixation vulnerabilities.
Some medical polymers--oddly enough--are more supple than metals and can help improve osteointegration
Thus, a modification of the surface of Ti implant, which will promote a higher osteointegration
of such implants, is essential.
Pennsylvania State University, Hydroxyapatite Nanotopographies to Enhance Allograft Osteointegration
The British firm's femoral device is appropriately dense in areas where stiffness and strength are required, but it also has strong lattice structures that encourage osteointegration
As a secondary effect of its antimicrobial action, PDT can promote bone formation leading to osteointegration
It is due to the high surface roughness of the metal substrate -- necessary for a good osteointegration
-- compared to the HA thickness.
These results indicate that the invasion of surrounding bone cells and thus osteointegration
make the HA-coated PA12/CF composite stem a promising hip replacement candidate.
The two major research fields approached in achieving these goals are: bioengineering--identification of new biomaterials in order to permit a better osteointegration
, and the second one is the development of better implant designs to assure a better biomechanical force transfer between implant and receptor bone.
A good osteointegration
is capable of offering this kind of fixation between the stem and the bone (Ghiba et al.
So, the incorporation of bioactive fillers such as HA in SEVA-C, aims not only to improve the in vivo osteointegration
of the implant, but also to act as a reinforcement of the blend, improving the stiffness to values within the typical range of human cortical bone.
Clinical studies have demonstrated excellent osteointegration
and a Bone Implant Contact BIC of 95% in 26 weeks.