osteodystrophy


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osteodystrophy

 [os″te-o-dis´trŏ-fe]
abnormal development of bone.
renal osteodystrophy a condition due to chronic kidney disease and renal failure, marked by impaired vitamin D metabolism, elevated serum phosphorus levels, low or normal serum calcium levels, and stimulation of parathyroid function. There may be any of various bone diseases, including osteitis fibrosa cystica, osteomalacia, osteoporosis, and sometimes osteosclerosis. If onset is in childhood, renal dwarfism may result.

os·te·o·dys·tro·phy

(os'tē-ō-dis'trō-fē),
Defective formation of bone.
Synonym(s): osteodystrophia
[osteo- + G. dys, difficult, imperfect, + trophē, nourishment]

osteodystrophy

/os·teo·dys·tro·phy/ (-dis´trah-fe) abnormal development of bone.
renal osteodystrophy  a condition due to chronic kidney disease and renal failure, with elevated serum phosphorus levels, low or normal serum calcium levels, and stimulation of parathyroid function, resulting in a variable admixture of bone disease.

osteodystrophy

[-dis′trəfē]
Etymology: Gk, osteon + dys, bad, trophe, nourishment
any generalized defect in bone development, usually associated with disturbances in calcium and phosphorus metabolism and renal insufficiency, such as in renal osteodystrophy. Also called osteodystrophia.

osteodystrophy

Orthopedics A general term for defective development of bone. See Renal Osteodystrophy.

os·te·o·dys·tro·phy

(os'tē-ō-dis'trŏ-fē)
Defective formation of bone; common in dogs with chronic nephritis.
Synonym(s): osteodystrophia.
[osteo- + G. dys, difficult, imperfect, + trophē, nourishment]

osteodystrophy

Defective bone formation.

osteodystrophy

defective bone formation
  • Albright's hereditary osteodystrophy pseudohypoparathyroidism (or pseudopseudohypoparathyroidism) with diabetes, hypertension, arteritis and polyarthrosis

  • renal osteodystrophy osteomalacia associated with chronic renal failure

os·te·o·dys·tro·phy

(os'tē-ō-dis'trŏ-fē)
Defective formation of bone.
[osteo- + G. dys, difficult, imperfect, + trophē, nourishment]

osteodystrophy

diseases of bone in which there is failure of normal development or abnormal metabolism in bone which is already mature. Principal clinical signs are distortion and enlargement of bones, susceptibility to fracture, and abnormalities of gait and posture. See also osteodystrophia fibrosa.

hypertrophic osteodystrophy
a disease of unknown etiology that occurs in young, rapidly growing dogs primarily of the large or giant breeds, in which there is pain and soft tissue swelling usually around the distal radius, ulna and tibia, lameness, and varying degrees of fever, lethargy and anorexia. Periosteal new bone is formed around the metaphyses and sometimes diaphyses, contributing to the enlargement of the limbs. The cause is unknown but hypovitaminosis C has at various times been suggested. Called also Möller-Barlow's disease (from a similar human disease), Barlow's disease, skeletal scurvy, infantile scurvy, osteodystrophy II, metaphyseal osteopathy, canine hypertrophic osteodystrophy.
renal osteodystrophy
see renal secondary hyperparathyroidism.
Enlarge picture
Hypertrophic osteodystrophy in a 4-month-old Great Dane. By permission from Lamb CR, Diagnostic Imaging of the Dog and Cat, Mosby, 1993
References in periodicals archive ?
2) Renal osteodystrophy, as in the patient presented here, is the term used to describe the combination of renal dysfunction coupled with hyperparathyroidism and the associated soft tissue and skeletal changes.
2) They reported on 17 resurfacing arthroplasties performed in patients with femoral deformities caused by trauma, renal osteodystrophy, proximal femoral focal deficiency, multiple epiphyseal dysplasia, and retained hardware.
0 SD below the mean for unaffected individuals) because of a combination of factors including poor growth during critical rapid growth periods such as the first 2 years of life and puberty, delayed, abbreviated puberty (with an attenuated growth rate), malnutrition, acidosis, and renal osteodystrophy.
Data from studies that investigated the effects of husbandry on calcium metabolism emphasize the importance of a proper diet (containing adequate calcium and vitamin D) and exposure to ultraviolet-B radiation in preventing osteodystrophy.
Secondary hyperparathyroidism is a serious complication of end-stage renal disease and can lead to renal osteodystrophy and other organ failure.
Principal treatment of renal anemia consists of effective dialysis, restoration of missing components (especially iron), control of renal osteodystrophy, as well as erythropoietin therapy.
Renal osteodystrophy, or bone disease of kidney failure, affects up to 90 percent of dialysis patients.
6,12) The congenital type is seen in rare syndromes, including congenital plaque-like osteomatosis, Albright hereditary osteodystrophy, fibrodysplasia ossificans progressiva, and osseous heteroplasia.
The hormone is secreted into the circulatory system to produce basal (healthy) concentrations of approximately 15-65 ng/L (1), and is assayed to assist in the diagnosis of hypo/hyperparathyroidism and hypercalcemia and in monitoring for renal osteodystrophy in patients with end-stage renal failure (1-3).