Curcumin in Combination with Piperine Suppresses Osteoclastogenesis
Capsaicin inhibits porphyromonas gingivalis growth, biofilm formation, gingivomucosal inflammatory cytokine secretion, and in vitro osteoclastogenesis
The second oral presentation titled "Different Effects of Abaloparatide and hPTH(1-34) on Osteoclastogenesis
and Bone Resorption" used data from preclinical studies of abaloparatide.
Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis
. Biochem Biophys Res Commun 1997; 234: 137-142, doi: 10.1006/bbrc.1997.6603.
Interaction between inflammation, TNF-[alpha] IL-6, and receptor activator of nuclear factor kappa B ligand (RANKL) modulates osteoclastogenesis
. In COA, TNF-[alpha] increases bone resorption because proinflammatory cytokines do not only increase RANKL expression, but increase osteoclastogenesis
in the presence of RANKL.
Proinflammatory cytokines such as TNF-[alpha] and the transcription factor-like receptor activator of the nuclear factor kappa ligand stimulate the osteoclastogenesis
which cause osteoporosis and fragility fractures.38 In this study, no significant differences were detected between the TNF-[alpha] inhibitor and NSAID groups in BMD values.
Experiments also (17) implicated CCL3 in multiple myeloma, a condition characterized by pathological osteoclastogenesis
Endogenous n-3 fatty acids protect ovariectomy induced bone loss by attenuating osteoclastogenesis
. J Cell Mol Med.
Induction of osteoclastogenesis
and bone loss by human autoantibodies against citrullinated vimentin.
(3) Therefore, interaction between OC precursors and OBs is vital to initiate osteoclastogenesis
. In our experiment, the presence of the OBs stimulated the formation of the OCs, probably by providing the stimuli required such as MCSF and RANKL.
In a research C57BL Db/db mice that developed diabetes at six to eight weeks of age to study decreased osteoclastogenesis
in bacteria-stimulated bone loss (He et al., 2004).
Well defines lines in BM25 shows early maturation and continuing osteogenesis, probably a result of inhibited osteoclastogenesis
. This effect is demonstrated in vitro in BM by Maurya et al.