"In the healthy adult population, about 30% of the circulating
osteocalcin occurs in its undercarboxylated form, and increased vitamin K intake results in rapid decline of ucOC, suggesting a state of subclinical vitamin K deficiency in healthy bone tissue.
In sensitivity analyses, in order to distinguish how biomarkers of bone resorption and bone formation influenced each other, the association of children's U-Cd at 9 y of age with urinary DPD (Model 1) was additionally adjusted for
osteocalcin, and the association of the U-Cd with
osteocalcin was additionally adjusted for DPD.
Studies in mice showed that moderate exercise, such as walking, triggers the release of
osteocalcin in the body.
BMD and serum intact
osteocalcin in postmenopausal osteoporosis women.
Osteocalcin was expressed in the cytoplasm of OSA and OPBT tumour cells (Figure 1) and also on the osteoid.
Lal, "Serum
osteocalcin as a diagnostic biomarker for primary osteoporosis in women," Journal of Clinical and Diagnostic Research, vol.
(2) Increased bone turnover was present if any of the following occurred in combination: serum
osteocalcin > 25.3 ng/ml and/or total alkaline phosphate > 130 U/L (bone formation marker) and urinary calcium excretion > 4 mg/kg/day.
The mineralized nodules and
osteocalcin levels were vital osteogenic indicators.
Undercarboxylated
osteocalcin (ucOC), a sensitive marker of vitamin K status, is correlated with age ([9,10]) and the risk of hip fracture in women ([10]).
Results: Homeostasis model assessment (HOMA)-IR, adiponectin,
osteocalcin, and androstenedione levels were significantly increased in the PCOS group.
Bone metabolism was evaluated by determining serum levels of
osteocalcin (OC) as a marker of bone formation, and urinary pyrilinks-D (PYD) and beta-CrossLaps (B-CTx) as markers of bone resorption (18).
We measured both C-telopeptide of type I collagen (CTX-I) and
osteocalcin levels via electrochemiluminescence immunoassay method.
