osteoblast


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

osteoblast

 [os´te-o-blast″]
a cell arising from a fibroblast, which, as it matures, is associated with bone production.

os·te·o·blast

(os'tē-ō-blast'),
A bone-forming cell that is derived from mesenchymal osteoprognitor cells and forms an osseous matrix in which it becomes enclosed as an osteocyte.
Synonym(s): osteoplast
[osteo- + G. blastos, germ]

osteoblast

(ŏs′tē-ə-blăst′)
n.
A cell from which bone develops; a bone-forming cell.

os′te·o·blas′tic adj.

osteoblast

A mononucleated fibroblast-derived cell that usually resides in bone and produces collagen I-rich osteoid, a matrix which, when calcified, is bone.

os·te·o·blast

(os'tē-ō-blast)
A bone-forming cell that is derived from mesenchymal progenitor cells and forms an osseous matrix in which it becomes enclosed as an osteocyte.
[osteo- + G. blastos, germ]

osteoblast

A bone-building cell. Osteoblasts are continuously active remodelling bone that has been broken down by OSTEOCLASTS.

osteoblast

a cell that produces the calcified intercellular material of bone. See also PERIOSTEUM.

Osteoblast

Bone-forming cell.
Mentioned in: Multiple Myeloma

os·te·o·blast

(os'tē-ō-blast)
A bone-forming cell derived from mesenchymal osteoprognitor cells that forms an osseous matrix in which it becomes enclosed as an osteocyte.
[osteo- + G. blastos, germ]
References in periodicals archive ?
A, Osteoblast specific protein expression detected by western blot.
Effects of 17[sz]-estradiol on Mitophagy in the murine MC3T3-E1 osteoblast cell line is mediated via G protein-coupled estrogen receptor and the ERK1/2 signaling pathway.
(1) The dynamic process of bone formation and resorption, also called "bone remodeling", is governed by 2 cell types: osteoblasts (OBs) and osteoclasts (OCs).
Jinno et al., "Bone morphogenetic protein 2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6," Molecular and Cellular Biology, vol.
The overall expression pattern was described first, followed by time series analysis, generation of modules by weighted gene coexpression network analysis, and identification of markers for osteoblast differentiation (Supplementary Figure 1).
In prethymic stage, mature osteoblast is indispensable for the production of thymus-seeding progenitors of T cell.
OC is the most specific gene for the osteoblast differentiation and mineralization.
miR-194 promotes osteoblast differentiation and activity in studies performed on mouse bone mesenchymal stem cell (BMSCs) cultures, by regulating Runx2 nuclear translocation through STAT1 inhibition and by downregulating COUP-TFII mRNA levels, therefore driving mesenchymal cell differentiation towards osteoblasts instead of adipocytes [52, 53].
Osteoblast Differentiation Pattern on Ti Surface with Different Modification
When the primary human osteoblasts (hOST) were seeded and cultured directly on the Ultrafoam[R], confocal microscopy showed CytotrackerTM Orange labeled cells to be predominantly on or close to the surface of the scaffold (Fig 5b panels 1i, 1ii).
Both PTH and PTHrP initiate their effects by binding with equal affinity to the same G-protein-coupled PTH receptor 1 (PTH1R), which is expressed on the surface of osteoblasts and osteocytes in bone, and tubular cells in the kidney (Silva & Bilezikian, 2015).