In the six months after Hurricanes Katrina and Rita made landfall, we noted three cases of
osmotic nephrosis secondary to IVIG--a diagnosis that was very rare at our hospital prior to the hurricanes.
Immune Globulin Intravenous (Human) (IGIV) products have been reported to be associated with renal dysfunction, acute renal failure,
osmotic nephrosis, and death.
It also appears to be capable of producing acute tubular injury, leading to
osmotic nephrosis and acute tubular necrosis.
Renal dysfunction, acute renal failure,
osmotic nephrosis, and death may occur with immune globulin intravenous (IGIV) products in predisposed patients.
IVIG products have been associated with renal dysfunction, acute renal failure,
osmotic nephrosis, and death.
Immune Globulin Intravenous (Human) products have been reported to be associated with renal dysfunction, acute renal failure,
osmotic nephrosis and death.
WARNING: Renal dysfunction, acute renal failure,
osmotic nephrosis, and death may be associated with the administration of Immune Globulin Intravenous (Human) (IVIg) products in predisposed patients.
