osmotic demyelination syndrome


Also found in: Acronyms, Wikipedia.

osmotic demyelination syndrome

(oz-mot'ik de-mi?e-li-na'shon)
Damage to the myelin sheaths that surround nerves, usually as a result of excessively rapid correction of very low serum sodium levels.

Patient care

It can be prevented by carefully monitoring serum sodium (Na+) concentrations when hyponatremic patients are rehydrated, limiting the increase in Na+ concentration to less than 10 meq/L in the first 24 hours, and 18meq/L in the first 2 days.

Synonym: myelinolysis
Mentioned in ?