Review of literature has suggested that the osmolal
gap can be increased in patients with ethanol-induced acidosis without the presence of other alcohols,  presumably owing to the presence of acetone, which is produced by ethanol metabolism and by starvation .
Contrast was subdivided on the basis of ionicity into ionic and nonionic; osmolarity into high osmolal
contrast media (HOCM) and low osmolal
contrast media (LOCM); structure into monomer and dimer.
2) In addition to screening tests for toxins, calculation of the osmolal
gap (OG) as osmolality - (2[Na+] + [urea] + [glucose]), may be helpful as an indicator of intoxication.
Anion and osmolal
gaps in the diagnosis of methanol poisoning: clinical study in 28 patients.
3 (B) Serum bicarbonate < 20 meq/L (C) Osmolal
gap > 10 mOsm/L (D) Urinary oxalate crystals present (in the case of EG poisoning) Data are from the American Academy of Clinical Toxicology Ad Hoc Committee on the Treatment Guidelines for Ethylene Glycol and Methanol Poisoning.
means roughly 'osmotically effective moles of solute per kg of water'.
The serum osmolal
gap (75 mOsm/kg) was calculated as follows: Osmolal
gap = freezing-point depression osmometer value --(2 X [[Na.
Serum sodium and osmolal
changes in tuberculous meningitis.
AKA can also be associated with other laboratory abnormalities, such as increased serum lactate and an osmolal
gap, as well as reduced electrolyte concentrations.
Severe acute VPA toxicity may be characterized by several biochemical abnormalities, including hyperammonemia, hypernatremia, hypocalcemia, an increased osmolal
and anion gap, respiratory alkalosis, metabolic acidosis, and increased transaminase activity.