oseltamivir


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Related to oseltamivir: Zanamivir

oseltamivir

 [o″sel-tam´ĭ-vir]
an inhibitor of viral neuraminidase, used as the phosphate salt in the treatment of influenza.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

oseltamivir

(ō′sĕl′tăm′ə-vîr′)
n.
An antiviral drug, C16H28N2O4, used in its phosphate form for the treatment and prevention of influenza.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

oseltamivir

An antiviral ingested as a prodrug, which is used to manage influenza A or B. A Cochrane review published in 2009 found no clear benefit for oseltamivir if taken after the first 24 hours.
 
Adverse events
Nausea, vomiting, diarrhoea, abdominal pain, and headache.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

oseltamivir

Tamiflu® Infectious disease An antiviral used for acute influenza type A and B Adverse events N&V. See Influenza.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The study also showed the efficacy of Xofluza to be comparable to oseltamivir (a proven effective treatment for children with the flu).
MINISTONE-2 is a phase III, multicentre, randomised, double-blind study that evaluated the safety, pharmacokinetics and efficacy of one dose of Xofluza compared with oseltamivir in otherwise healthy children aged one to less than 12 years with influenza infection and displaying influenza symptoms (temperature of 38[degree sign]C or over, and one or more respiratory symptom).
But in a decision dated July 4 resolving the petition for review of the GSIS' board of trustees, the COA said the purchase of 476,300 Oseltamivir capsules was not part of GSIS' mandate since it is a social insurance institution and not a health agency.
Bradley noted baloxavir is much more expensive than oseltamivir, which may not justify the better tolerance of the drug for influenza treatment.
"Single-dose baloxavir was without evident safety concerns, was superior to placebo in alleviating influenza symptoms, and was superior to both oseltamivir and placebo in reducing the viral load one day after initiation of the trial regimen in patients with uncomplicated influenza," the authors write.
Oseltamivir phosphate is intended for use in patients 2 weeks of age and older who have had flu symptoms for no more than 48 hours, and for prevention of influenza in patients 1 year of age and older.
(3,4) This data makes the clinician alert to the problem and prompt to prescribe oseltamivir when facing a flu syndrome.
Oseltamivir (Tamiflu[R], Roche-Korea), purchased from a pharmacy in Korea as prescribed by a medical doctor was used as positive control.
A 2014 systematic review included 8 RCTs in adults (3954 patients) and one RCT in children (669 patients) with influenza and compared time to alleviation of symptoms with oseltamivir and placebo.
Keywords: Critically ill child, influenza, oseltamivir, pediatric intensive care
A lively, and sometimes heated, debate has recently been conducted in the popular press (1) and medical literature (2-4) about the effectiveness of oseltamivir, its usefulness in treating seasonal influenza, and the need for it to be stockpiled for use in a future influenza pandemic.