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(or-thof″thăl-al′dĭ-hīd″) [ ortho- + (na)phthal(ene) + aldehyde],


A microbicidal chemical used to disinfect surfaces, endoscopes, and other heat-sensitive instruments.


Personnel who use OPA must wear gloves, goggles, and gowns to prevent contact with mucous membranes or skin.
CAS # 643-79-8
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References in periodicals archive ?
Levels of serotonin bound to platelets and free in plasma in jugular and forearm venous blood as determined by a fluorescent-OPT (orthophthalaldehyde) assay.
Several methods are suitable for the determination of amino acids (AAs) in biological fluids, including gas chromatography [1,2], reversed-phase chromatography with precolumn derivatization with various reagents such as orthophthalaldehyde (OPA) [3-6], 9-fluorenylmethyl-chloroformate [7], phenylisothiocyanate (PITC) [8, 9], dimethylaminonaphthalenesulfonyl chloride [10], dimethylaminoazobenzenesulfonyl chloride [10], 4-fluoro7-nitrobenzo-2-oxa-1,3-diazole [11], and ion-exchange chromatography with postcolumn derivatization utilizing OPA [12] or ninhydrin [13,14].
Plasma amino acid determinations by reversed-phase HPLC: improvement of the orthophthalaldehyde method and comparison with ion-exchange chromatography.