Mx protein has been found in a wide range of species and enables the resistant activity to orthomyxovirus
(Haller et al., 1998; Lee and Vidal, 2002).
In 2010 in Australia, an orthomyxovirus
with genetic and antigenic properties similar to WFBV (designated as Cygnet River virus [CyRV]) was isolated during an outbreak of salmonellosis (Salmonella enterica serovar Typhimurium) in Muscovy ducks (Cairina moschata) on Kangaroo Island, South Australia (10).
HRTV could potentially circulate without the need for actual replication in the vertebrate host through direct tick-to-tick transmission while co-feeding nearby on a vertebrate host, as described for the orthomyxovirus
, Thogoto virus (36).
To compare classical and modern experimental approaches of virus purification and enrichment, we designed a tissue model for internal organs of chicken, each infected with 1 of 4 viruses (poxvirus [vaccinia virus], reovirus [orthoreovirus], orthomyxovirus
[influenza virus], and paramyxovirus [Sendai virus]) at low concentrations (Table 1; Table 2, http://wwnc.cdc.gov/EID/article/21/1/14-0766-T2.htm; online Technical Appendix, http://wwnc.cdc.gov/EID/article/21/1/14-0766-Techapp1.pdf).
We identified a novel orthomyxovirus
virus isolated from Muscovy ducks in South Australia.
Influenza A virus, a member of the genus Orthomyxovirus
, is an economically important virus that causes disease in humans, pigs, horses, and fowl (1).
The single isolate of DHOV, another member of the tickborne orthomyxovirus
group, was obtained from a pool of R.