orphenadrine citrate


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orphenadrine citrate

[ôrfen′ədrēn]
a skeletal muscle relaxant with anticholinergic and antihistaminic activity.
indication It is prescribed in the treatment of severe muscle strain.
contraindications Myasthenia gravis, glaucoma or other contraindications to anticholinergic agents, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the most serious adverse effects are those associated with anticholinergic activity, such as dry mouth and tachycardia, and allergic reactions.
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In 100 ml measuring flask 50 mg of Orphenadrine citrate was transferred, added 80 ml mobile phase, sonicated to dissolve and again mobile phase was added to made volume up to the mark.
An accurately weigh amount of powdered drug equivalent to 450 mg of Paracetamol, 50 mg of Orphenadrine citrate and 30 mg of Caffeine was transferred in 100 ml volumetric flask and added 80 ml of mobile phase, sonicated to dissolve and again mobile phase was added to made volume up to the mark.
30 mg of Caffeine, 450 mg of Paracetamol and 50 mg of Orphenadrine citrate was added in 100 ml volumetric flask and 80 ml of mobile phase was added, sonicated to dissolve and volume was up to the mark with mobile phase.
100 % and 120 %) of Paracetamol, Caffeine and Orphenadrine citrate.
To prove the sufficiency of the method, a laboratory mixture of Paracetamol, Caffeine and Orphenadrine citrate was prepared.
The specificity of the method, Paracetamol RS (single APIs 100 %), Caffeine RS (single APIs 100 %), and Orphenadrine citrate RS (single APIs 100 %) solutions were prepared.
No interference was found from placebo at the retention time of Paracetamol, Caffeine and Orphenadrine citrate.