orotic acid


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orotic acid

 [o-rot´ik]
an intermediate in the biosynthesis of pyrimidine nucleotides.

o·rot·ic ac·id (Oro),

(ōr-ot'ik as'id),
6-Carboxyuracil; uracil-6-carboxylic acid; an important intermediate in the formation of the pyrimidine nucleotides; elevated in certain inherited defects of pyrimidine biosynthesis.

orotic acid

[ôrot′ik]
a pyrimidine synthesized in the cell from carboxyl phosphate and aspartic acid by means of condensation, dehydration, and oxidation.

o·rot·ic ac·id

(ōr-ot'ik as'id)
An important intermediate in the formation of the pyrimidine nucleotides; elevated in certain inherited defects of pyrimidine biosynthesis.

orotic acid

an intermediate in the biosynthesis of pyrimidine nucleotides.
References in periodicals archive ?
Rapid determination of orotic acid in urine by liquid chromatography-electrospray tandem mass spectrometry.
Determination of urinary orotic acid and uracil by capillary zone electrophoresis.
Automated determination of orotic acid, uracil and pseudouridine in urine by highperformance liquid chromatography with column switching.
These defects can be diagnosed on basis of the increased concentrations of orotic acid in urine.
The enzyme converts orotic acid and 5-phospho-[alpha]-D-ribosyl-1-pyrophosphate into orotidine 5-phosphate.
A new stable-isotope dilution method for measurement of orotic acid using solvent-extracted urine.