orotic acid


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia, Wikipedia.

orotic acid

 [o-rot´ik]
an intermediate in the biosynthesis of pyrimidine nucleotides.

o·rot·ic ac·id (Oro),

(ōr-ot'ik as'id),
6-Carboxyuracil; uracil-6-carboxylic acid; an important intermediate in the formation of the pyrimidine nucleotides; elevated in certain inherited defects of pyrimidine biosynthesis.

orotic acid

[ôrot′ik]
a pyrimidine synthesized in the cell from carboxyl phosphate and aspartic acid by means of condensation, dehydration, and oxidation.

o·rot·ic ac·id

(ōr-ot'ik as'id)
An important intermediate in the formation of the pyrimidine nucleotides; elevated in certain inherited defects of pyrimidine biosynthesis.

orotic acid

an intermediate in the biosynthesis of pyrimidine nucleotides.
References in periodicals archive ?
Automated determination of orotic acid, uracil and pseudouridine in urine by highperformance liquid chromatography with column switching.
The enzyme converts orotic acid and 5-phospho-[alpha]-D-ribosyl-1-pyrophosphate into orotidine 5-phosphate.
Urinary excretion of orotic acid, orotidine and other pyrimidines in a patient with purine nucleotide phosphorylase deficiency.
A new stable-isotope dilution method for measurement of orotic acid using solvent-extracted urine.