oropharyngeal cancer


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oropharyngeal cancer

ENT A malignancy of the lips, tongue, floor of mouth, salivary glands, buccal mucosa, gingiva, palate, and throat; most are SCCs linked to tobacco use and/or smoking, and tend to spread rapidly High risk factors Alcohol abuse, poor dental and oral hygiene, chronic irritation–eg, rough teeth, dentures, etc; OCs begin as leukoplakia or mouth ulcers; 2:1, ♂:♀. See Squamous cell carcinoma.
Oropharyngeal cancer-Stages
I   Lesion is ≤ 2 cm and confined to the oropharynx
II   Lesion is between 2 cm and 4 cm and confined to the oropharynx
III  Lesion is ≥ 4 cm and may involve a single lymph node on same side of neck
IV  Lesion has spread to the hard palate, tongue, or larynx, to nearby lymph nodes, or metastasized
References in periodicals archive ?
Traditionally, oropharyngeal cancers have been associated with smoking and alcohol; however, it is now understood that HPV is an emerging causal factor in oropharyngeal cancer.
12) Even conservative predictions estimate that 70 percent of oropharyngeal cancers in 2020 will be HPV positive.
length of practice, practice setting etc) with the knowledge about the vaccine, knowledge about HPV associated oropharyngeal cancer, and recommendation of the HPV vaccine for males.
The report provides a snapshot of the global therapeutic landscape of Oropharyngeal Cancer
It is estimated that the prevalence of HPV in patients with oropharyngeal cancer is about 36%, with HPV16 being the commonest type (~86%) in all HPV-positive (HPV+) tumors (8).
The association between T-stage and clinical nodal metastasis In HPV-positive oropharyngeal cancer.
20) Theoretically, the 9-valent vaccine, with protection against HPV types 16, 18, 31, 33, 45, and 52, may be an optimal choice to prevent HPV-induced oropharyngeal cancer because of its broad coverage.
1) Data shows that oropharyngeal cancers are becoming more prevalent in younger adults with no history of smoking or drinking.
Tobacco smoking and increased risk of death and progression for patients with p16-positive and p16-negative oropharyngeal cancer.
In addition to tobacco use and alcohol use, infection with human papillomavirus (HPV) has been recognized as an independent risk factor for oropharyngeal cancer (3-6).
Oropharyngeal Cancer - Pipeline Review, Half Year is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team.
Fortunately, HPV associated oropharyngeal cancer actually carries a much better prognosis than does a cancer in this location that is not associated with HPV.