Diagnosis: Based upon the history and clinical examination, a provisional diagnosis of mandibular hypo- and hyperdontia and chronic generalised gingivitis was made and the differential diagnosis of orodigitofacial dysostosis, Hallerman Streiff and Cleidocranial dysplasia syndromes were considered.
Hypo-hyperdontia is rare in isolation and has been associated with over 50 syndromes, notably orodigitofacial dysostosis, Hallerman Streiff, cleidocranial dysplasia syndrome, Ellis van Creveld, Down syndrome, cleft lip and palate, and many others [Zhu et al., 1996; Anthonappa et al., 2008; Varela et al., 2009].