ornithine delta-aminotransferase

or·ni·thine δ-·a·mi·no·trans·fer·ase

an enzyme that will reversibly catalyze the reaction of α-ketoglutarate and l-ornithine to form l-glutamate and l-glutamate γ-semialdehyde; a deficiency of this enzyme will result in gyrate atrophy of the choroid and retina.
References in periodicals archive ?
Verma, "Cloning of ornithine delta-aminotransferase cDNA from Vigna aconitifolia by trans-complementation in Escherichia coli and regulation of proline biosynthesis," The Journal of Biological Chemistry, vol.
Several animal models of RPE degeneration, such as sodium iodate-induced mouse, rat, and rabbit models [7-9], the ornithine-induced rat model [10], and the ornithine delta-aminotransferase deficient mouse [11], have been established and used in studies of the mechanisms of dry AMD and gyrate atrophy.
In fact, similar changes were reported in other animal models of RPE degeneration, including sodium iodate [7] and ornithine-induced models [10] and the ornithine delta-aminotransferase deficient mouse [11], and a similar scenario also has been invoked as a mechanism in human dry AMD [2,3] and gyrate atrophy [4].
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