organ-confined disease

organ-confined disease

An illness, such as a tumor or an abscess, that has not spread beyond the organ in which it originated. One example is prostate cancer that is confined within the prostate gland and has not entered the seminal vesicles or pelvic lymph nodes.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
The output variables are transformed using the guidelines of the American Joint Committee on Cancer (AJCC), which were used to identify the pathologic stage as organ-confined disease (OCD; pT2+) or non-organ-confined disease (NOCD; pT3+ or N+) [23].
These authors did not detect difference in preoperative and pathologic predictors of organ-confined disease and BCR between men aged <50 years and older [14].
(4,5) In RCC, nephron-sparing surgery is advocated in organ-confined disease where previously RN would have been routine practice.
(9,10) PSA testing had a significant impact in diagnosing early, organ-confined disease (11) despite low sensitivity and specificity.
(3) Also in our opinion, patients with truly clinically organ-confined disease may be reserved for adjuvant chemotherapy (AC); because at least in theoretical basis AC should be equally effective as NAC in this group of patients.
Among the enrolled patients, 302 were diagnosed with organ-confined disease (T1-2N0 M0), whereas 56 had a distant metastasis (any T, any N, and M1).
But now, the rise in rates of cure because of the likelihood of having an organ-confined disease has ended.
The results support findings from a previous longitudinal, population-based study of nearly 29,000 men that suggested obesity may protect against development of organ-confined disease. This does not mean that it's okay to be obese, he cautioned.
(six months post-treatment, organ-confined disease, Internet user/online support, 40-50 years) That's how men are.
They found that a ratio of free to total PSA less than 0.0765 could distinguish patients with extracapsular extension (ECE) from those with organ-confined disease (OCD), with a sensitivity of 100% and a specificity of 93%.
We have no similar system with males that sort of says, "Well, every couple of years you go and see a doctor." (Six months post-treatment, organ-confined disease, 40-50 years) This sort of macho thing....
In patients with organ-confined disease (pT1a-pT2b), PSA and hK2 were detected in 6 of 10 patients, whereas 3 patients were negative for both PSA and hK2 mRNA.