organ-confined disease

An illness, such as a tumor or an abscess, that has not spread beyond the organ in which it originated. One example is prostate cancer that is confined within the prostate gland and has not entered the seminal vesicles or pelvic lymph nodes.

References in periodicals archive ?

The output variables are transformed using the guidelines of the American Joint Committee on Cancer (AJCC), which were used to identify the pathologic stage as organ-confined disease (OCD; pT2+) or non-organ-confined disease (NOCD; pT3+ or N+) [23].

A Deep Belief Network and Dempster-Shafer-Based Multiclassifier for the Pathology Stage of Prostate Cancer

These authors did not detect difference in preoperative and pathologic predictors of organ-confined disease and BCR between men aged <50 years and older [14].

Long-Term Oncological Outcomes for Young Men Undergoing Radical Prostatectomy for Localized Prostate Cancer

(4,5) In RCC, nephron-sparing surgery is advocated in organ-confined disease where previously RN would have been routine practice.

Comparative effectiveness of adrenal sparing radical nephrectomy and non-adrenal sparing radical nephrectomy in clear cell renal cell carcinoma: observational study of survival outcomes

(9,10) PSA testing had a significant impact in diagnosing early, organ-confined disease (11) despite low sensitivity and specificity.

Prostate cancer diagnostic options: past present and future

(3) Also in our opinion, patients with truly clinically organ-confined disease may be reserved for adjuvant chemotherapy (AC); because at least in theoretical basis AC should be equally effective as NAC in this group of patients.

Re: The feasibility of radical cystectomy in elderly patients

Among the enrolled patients, 302 were diagnosed with organ-confined disease (T1-2N0 M0), whereas 56 had a distant metastasis (any T, any N, and M1).

Preoperative butyrylcholinesterase level as an independent predictor of overall survival in clear cell renal cell carcinoma patients treated with nephrectomy

But now, the rise in rates of cure because of the likelihood of having an organ-confined disease has ended.

Early prostate cancer detection hits a plateau

The results support findings from a previous longitudinal, population-based study of nearly 29,000 men that suggested obesity may protect against development of organ-confined disease. This does not mean that it's okay to be obese, he cautioned.

Data are mixed on impact of obesity on prostate cancer

(six months post-treatment, organ-confined disease, Internet user/online support, 40-50 years) That's how men are.

The eMale: prostate cancer, masculinity and online support as a challenge to medical expertise

They found that a ratio of free to total PSA less than 0.0765 could distinguish patients with extracapsular extension (ECE) from those with organ-confined disease (OCD), with a sensitivity of 100% and a specificity of 93%.

PSA ratio useful in spotting advanced prostate cancer

We have no similar system with males that sort of says, "Well, every couple of years you go and see a doctor." (Six months post-treatment, organ-confined disease, 40-50 years) This sort of macho thing....

Prostate cancer and masculinity in Australian society: a case of stolen identity?

In patients with organ-confined disease (pT1a-pT2b), PSA and hK2 were detected in 6 of 10 patients, whereas 3 patients were negative for both PSA and hK2 mRNA.

Simultaneous quantification of prostate-specific antigen and human glandular kallikrein 2 mRNA in blood samples from patients with prostate cancer and benign disease