orbitofrontal cortex


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or·bi·to·fron·tal cor·tex

the cerebral cortex covering the basal surface of the frontal lobes.
Synonym(s): frontoorbital area
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The focus of the fMRI analysis was on brain regions implicated in reward and reward valuation, including the orbitofrontal cortex, dorsolateral prefrontal cortex, striatum (caudate, nucleus accumbens, putamen), insula, midbrain, and amygdala, as these regions are activated by desire and rewarding experience, such as consuming high-sugar food.
In a recent study, researchers found that stimulating a part of the brain called the orbitofrontal cortex may lead to significant improvements in mood for people with moderate-to-severe depression.
-Subcaudate Tractotomy (Innominatomy): The location of the thermocoagulative lesions of this surgical treatment is described as immediately below the head of the caudate nucleus (7-15 mm lateral to the midline of the posteromedial orbitofrontal cortex, i.
Further, the researchers analysed responses in two brain regions that motivate eating behaviour: the nucleus accumbens (NAcc) and the orbitofrontal cortex (OFC).
Stimulation of a brain region called the lateral orbitofrontal cortex (OFC) reliably produced acute improvement in mood in patients who suffered from depression at the start of the study.
A great number of dissimilar structures take part in identifying the emotion shown in a face: the occipito-temporal cortices, amygdala, orbitofrontal cortex, basal ganglia, and right parietal cortices, along with others.
The neural connectivity of the CN to the medial prefrontal cortex [Brodmann area (BA): 10, 12] and the orbitofrontal cortex (BA: 11, 13) had disappeared in both hemispheres.
There was also a correlation for compassion training-related increases in visual preference for suffering with decreases in regions sensitive to valence and empathic distress, spanning the anterior insula and orbitofrontal cortex; the opposite effect was seen in the reappraisal group.
(19) Neurons in the orbitofrontal cortex (OFC) signal the value of social information; in the OFC, neurons conveying social information were more prevalent than neurons conveying information regarding fluid rewards.
First, they found that ACEs are associated with (1) morphological changes in the anterior cingulate, dorsolateral prefrontal and orbitofrontal cortex, corpus callosum, and adult hippocampus and (2) functional changes, such as enhanced amygdala response to emotional faces and diminished striatal response to anticipated rewards.