Idiopathic orbital pseudotumor
is characterized by the presence of non-granulomatous inflammation in the eye without a known systemic or local reason.
Pathologic involvement beyond the cavernous sinus, superior orbital fissure, or apex of the orbit occurs rarely, and the disorder is part of a continuum with idiopathic orbital pseudotumor
, with which it shares histopathology features.
Painful ophthalmoplegia is the consequence of the mass effect on the cavernous sinus which includes trauma, vascular malformation, neoplasm, infection, and inflammation including Tolosa-Hunt syndrome, Wegener's granulomatosis, or orbital pseudotumor
Marenco de la Fuente, "Resistant orbital pseudotumor
treated with rituximab in a patient with systemic lupus erythematosus.
with cavernous sinus and sellar extension.
4,7 Due to this slow onset clinic, indirect variety may be mistaken for chronic conjunctivitis, orbital pseudotumor
, orbital cellulitis or thyroid disease.
Much of what is known about pseudotumors has been gleaned from the ophthalmology literature-particularly, from discussions of the more common orbital pseudotumor
Sclerosing orbital pseudotumor
is a unique subtype of inflammatory orbital pseudotumor
, which is a fibro-inflammatory mass arising in the orbit without any identifiable cause such as infection, cancer, or a systemic inflammatory disorder (e.
Idiopathic inflammatory orbital pseudotumor
in childhood: II: results of diagnostic tests and biopsies.
3-8) Differential diagnosis includes thyroid eye disease, orbital pseudotumor
, orbital cellulitis, benign or malignant orbital tumors, encephalocele, or meningocele.
This condition has also been associated with such disorders as Riedel thyroiditis, orbital pseudotumor
, sclerosing cholangitis, and retroperitoneal fibrosis.
3] It has also been described as part of multifocal or systemic fibrosclerosis, a disease spectrum that also includes retroperitoneal fibrosis, sclerosing mediastinitis, Riedel thyroiditis, and orbital pseudotumor