Treatment also included orbifloxacin
(20 mg/kg PO q24h for 21 days; Orbax, Merck Animal Health, Madison, NJ, USA), meloxicam (0.
Comparative serum pharmacokinetic of the fluoroquinolones Enrofloxacin, difloxacin, marbofloxacin and orbifloxacin
in dogs after single oral administration.
Approaches for application of sub and supercritical fluid extraction f or quantification of orbifloxacin
from plasma and milk: Application to disposition kinetics.
Efficacy of orbifloxacin
tablets for the treatment of superficial and deep pyoderma due to Staphylococcus intermedius infections in dogs.
Quinolone antimicrobial drugs available for use in companion animals in Australia under the authority of the Pharmaceutical Benefits Scheme Drug (date registered) Indication Difloxacin (2001) Treatment of infections in dogs caused by difloxacin-sensitive organisms Enrofloxacin (2004) Treatment of urinary and respiratory tract infections, deep pyodermas, wounds, abscesses, and discharging sinuses in dogs caused by enrofloxacin-susceptible bacteria Orbifloxacin
(1999) Treatment of diseases in dogs and cats caused by orbifloxacin
-sensitive bacteria Ibafloxacin (2007) Treatment of urinary tract, respiratory tract, skin, and soft tissue infections in dogs and cats caused by ibafloxacin-sensitive bacteria
, danofloxacin, pipemidic acid, mathofloxacin, lomefloxacin, pefloxacin, enrofloxacin, norfloxacin, ciprofloxacin, and ofloxacin were purchased from Sigma (St.
Pharmacokinetics and milk penetration of orbifloxacin
after intravenous, intramuscular and subcutaneous administration in lactating goats.
The treatment protocol consisted of orbifloxacin
(30 mg/kg PO q12h X 16 days), meloxicam (0.
4,5,7,10,11,20,23) Rapid clearance of orbifloxacin
also was reported in quail by Hawkins et al.