oral hairy leukoplakia

(redirected from oral warts)


a disease marked by the development of white thickened patches on the mucous membranes of the cheeks (leukoplakia buccalis), gums, or tongue (leukoplakia lingualis); the patches sometimes form fissures and often become malignant. They may grow into larger patches or form ulcers. Those in the mouth may in time cause pain during swallowing of food or speaking. Leukoplakia affects mostly middle-aged to elderly men, often after prolonged irritation of the mouth from such varying factors as badly fitting dentures or immoderate use of tobacco.

Treatment is aimed at removing any possible cause of physical or chemical irritation; the patient should give up tobacco and possibly also alcohol and extremely hot food. Dental attention may be necessary if teeth are uneven or dentures do not fit properly. Surgical removal of the affected area is relatively simple and may be the best means of preventing further development of the condition.
oral hairy leukoplakia a white filiform to flat patch occurring on the tongue or, rarely, on the buccal mucosa, caused by infection with Epstein-Barr virus and associated with human immunodeficiency virus infection.
leukoplakia vul´vae the presence of hypertrophic grayish-white infiltrated patches on the vulvar mucosa; specific diagnosis is determined by biopsy.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
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oral hairy leukoplakia

Leukoplakia of the tongue. It is typically found in immunocompromised patients is a result of Epstein-Barr virus infection.
See also: leukoplakia
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Oral lesions especially oral candidiasis, necrotizing periodontal conditions, Kaposi sarcoma, oral hairy leukoplakia, oral warts and recurrent oral ulcers are essentially related to HIV/AIDS disease progression.1
But some lesions especially oral warts related to human papilloma virus (HPV) and oral ulcers, xerostomia, mucositis, hyperpigmentation, erythema multiforme and lichenoid reactions have been reported to be increased after ART attributed to the immune reconstitution, adverse effects of ART or drug resistance.6
The benign HPV-associated oral lesions, focal epithelial hyperplasia (Heck disease), oral squamous cell papilloma, oral verruca vulgaris (common wart) and oral condyloma acuminatum, are collectively referred to as oral warts. The majority of cases reported in the literature regarding to warts of the tongue and oral cavity include condyloma acuminatum caused by HPV types 6 and 116, 11, 12 [10].
Oral warts, papillomas, skin warts, and genital warts are associated with the human papilloma virus (HPV).
Unusual HPV types in oral warts in association with HIV infection.
The study in Romani population consisted of 173 children at age range 6 to 12 years, the most common oral and perioral lesions included: candidiasis (29%), ulcers (15%), salivary gland disease (9%), necrotizing ulcerative gingivitis/periodontitis (5%), linear gingival erythema (4%), labial molluscum contagiosum (3%), oral warts (2%), hairy leukoplakia (2%), and herpes zoster (1%).
The most frequently observed oral lesions were candidiasis (20.9%), especially in its pseudomembranous (PC) and erythematous forms, followed by periodontal disease (PD) (9.1%), oral hairy leukoplakia (OHL) (7.9%), recurrent aphthous ulcers (3.5%), Kaposi's sarcoma (KS) (0.8%), oral warts (1.2%), ulcer not otherwise specified (1%), lymphadenopathy (0.8%), HIV-associated salivary gland disease (SGD) (0.8%), labial herpes (0.8%) and necrotizing stomatitis (0.4%) (Table 1).
O'Brien's study follows a British report that concluded highly active antiretroviral therapy appears to increase the frequency of oral warts (Lancet 357[9266]: 1,411-12, 2001).
A review of the records from 1280 patients with HIV seen at a clinic between 1990 and 1999 indicates that the frequency of oral warts is increasing, despite the use of anti-HIV therapy.
(HPV is also responsible for the development of oral warts; see review on page 19).
The clinic also provides a unique experience for patients to participate in several research studies looking at topics like oral warts, oral Epstein-Barr virus infections, the effects and treatment of lipodystrophy in the oral cavity, and dental implants.
Oral opportunistic viral infections include herpes simplex infections, oral hairy leukoplakia, varicella-zoster infections, cytomegalovirus infections and oral warts. While the development of new antiretroviral therapies for the management of HIV infection, particularly protease inhibitors, has resulted in a decreased prevalence of certain oral diseases such as hairy leukoplakia and necrotizing periodontitis, a paradoxical increase in oral warts has been observed.[2,3]