oral glucose tolerance test

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oral glucose tolerance test



A screening test for diabetes mellitus (DM), in which plasma glucose levels are measured after the patient consumes an oral glucose load. In screening patients for type 2 DM, measuring fasting plasma glucose levels or checking a hemoglobin A1c level is generally preferable to an OGTT because the former tests are simpler, cheaper, and better tolerated by patients. An OGTT reveals type 2 DM when plasma glucose levels exceed 200 mg/dl 2 hr after drinking a 75-g glucose load. Plasma glucose levels between 140 mg/dl and 199 mg/dl suggest impaired glucose tolerance.

Gestational Diabetes Mellitus

In pregnancy, a modified OGTT is used to screen women with risk factors for gestational diabetes (GDM), including obesity, family history of type 2 DM, age greater than 25 years, and a history of unexplained stillbirths. At 24 to 28 weeks' gestation, a 50-g glucose load is given; 1-hr plasma glucose levels greater than 140 mg/dl constitute a positive screening result. Any patient having a positive test result should then undergo a 2-hr, 100-g OGTT to determine whether GDM is present. See: table

Screen high-risk women at first visit, and screen all women at 24–28 weeks' gestation with 75g oral glucose tolerance test. American Diabetes Association revised Standards of Medical Care, published in Diabetes Care special supplement, January 2011. International Association of Diabetes and Pregnancy Study Groups published in Leary, J. et al. (2010). Best Practice Research Clinical Endocrinology and Metabolism 24 (4), 673.
Time:Glucose level exceeds:
Fasting92 mg/dl
60 min180 mg/dl
120 min155 mg/dl
180 min140 mg/dl
References in periodicals archive ?
However, an oral glucose tolerance test may not be feasible in all clinical settings, which is why "the AACE statement did not make it mandatory but, based on the same evidence, settled for the directive to look for type 2 diabetes, impaired fasting glucose, or impaired glucose tolerance in all PCOS women, using whatever method possible," Dr.
If the glucose level is below 126 mg/dL but there is a high clinical suspicion of diabetes, the oral glucose tolerance test should be performed on a different day.
Although the results failed to support the study's primary hypothesis--that the 100-g oral glucose tolerance test (OGTT) would be more effective than the 75-g test for triggering the management steps that would prevent macrosomia--the findings did show that significantly fewer women were diagnosed with gestational diabetes by the 75-g test, compared with the 100-g test, Dr.
Among women with GDM, both the fasting glucose value of the oral glucose tolerance test and the infant's gestational age were associated with the percentage of body fat; among the nondiabetic mothers, maternal weight gain was the only predictor of percent body fat.
The following parameters were evaluated: homeostasis model assessment (HOMA)-IR, HOMA-[sz], modified [sz]-cell function index (MBCI), peak insulin/fasting insulin (I[sub]P/I[sub]0), AUC[sub]ins-OGTT, and AUC[sub]ins-OGTT/AUC[sub]glu-OGTTfrom the oral glucose tolerance test (OGTT) insulin release test were utilized to assess the second-phase insulin secretion, while the I[sub]P/I[sub]0, AIR[sub]0′~10′, and AUC[sub]ins-IVGTTfrom the intravenous glucose tolerance test (IVGTT) insulin release test were used to assess the first-phase insulin secretion.
Material and Methods: Pregnant women who presented in outpatient department of gynaecology between 24-34 weeks of gestation were randomly selected, and were requested to undergo 100 Gm oral glucose tolerance test for diagnosis of gestational diabetes mellitus (GDM).
They were given an oral glucose tolerance test, and were asked to estimate their chances of having undiagnosed diabetes using a six-category scale.
Doctors should add an oral glucose tolerance test (OGTT) to their hemoglobin A1C (HbA1C) when they screen high-risk children for prediabetes and diabetes, new South Korean research suggests.
In a subset of subjects, an oral glucose tolerance test is also being conducted at baseline and at the end of treatment.
Keywords: Gestational diabetes mellitus, oral glucose tolerance test, diagnostic criteria, prevalence
13) If patients were not diabetic, an Oral Glucose Tolerance Test (OGTT) was performed in the morning after an overnight fast as recommended by the National Diabetes Data Group.