oral glucose tolerance test

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oral glucose tolerance test



A screening test for diabetes mellitus (DM), in which plasma glucose levels are measured after the patient consumes an oral glucose load. In screening patients for type 2 DM, measuring fasting plasma glucose levels or checking a hemoglobin A1c level is generally preferable to an OGTT because the former tests are simpler, cheaper, and better tolerated by patients. An OGTT reveals type 2 DM when plasma glucose levels exceed 200 mg/dl 2 hr after drinking a 75-g glucose load. Plasma glucose levels between 140 mg/dl and 199 mg/dl suggest impaired glucose tolerance.

Gestational Diabetes Mellitus

In pregnancy, a modified OGTT is used to screen women with risk factors for gestational diabetes (GDM), including obesity, family history of type 2 DM, age greater than 25 years, and a history of unexplained stillbirths. At 24 to 28 weeks' gestation, a 50-g glucose load is given; 1-hr plasma glucose levels greater than 140 mg/dl constitute a positive screening result. Any patient having a positive test result should then undergo a 2-hr, 100-g OGTT to determine whether GDM is present. See: table

Screen high-risk women at first visit, and screen all women at 24–28 weeks' gestation with 75g oral glucose tolerance test. American Diabetes Association revised Standards of Medical Care, published in Diabetes Care special supplement, January 2011. International Association of Diabetes and Pregnancy Study Groups published in Leary, J. et al. (2010). Best Practice Research Clinical Endocrinology and Metabolism 24 (4), 673.
Time:Glucose level exceeds:
Fasting92 mg/dl
60 min180 mg/dl
120 min155 mg/dl
180 min140 mg/dl
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
The chart below contains the FPG test's blood glucose ranges for prediabetes and diabetes: Blood Glucose Range Diagnosis 100 to 125 mg/dL Prediabetes (also called Impaired Fasting Glucose) 126 mg/dl or more Diabetes mellitus (typs 2 diabetes) Oral Glucose Tolerance Test (OGTT) This test measures how well the body handles a standard amount of glucose.
During that period, NHANES conducted oral glucose tolerance tests of persons in that age group and estimated that 40% of adults aged 40-74 years had impaired fasting glucose, impaired glucose tolerance, or both (2).
Effects of oral glucosamine sulphate on serum glucose and insulin during an oral glucose tolerance test of subjects with osteoarthritis.
The first protocol was to continue the previously recommended 50-g glucose challenge test with a diagnostic 3-h 100-g oral glucose tolerance test (OGTT) if the glucose concentration was increased at 1 h after the 50-g load.
But when Dutch researchers gave 13 women with diabetes 1 1/2 grams of ground cinnamon (3/4 teaspoon) every day for six weeks, they did no better on an oral glucose tolerance test than similar women who were given a placebo.
The prior criteria for diagnosing diabetes relied heavily on performing an oral glucose tolerance test (OGTT).
In this criteria, two or more abnormal glucose values in the 3-h, 100-g oral glucose tolerance test (OGTT) were considered pathological (3).
In studies that involved those at high risk of the disease, magnesium supplementation was associated with significantly improved plasma glucose levels compared to a placebo following a two-hour oral glucose tolerance test and a trend toward reduced insulin resistance.
Gestational impaired glucose tolerance (IGT) is defined as an abnormal glucose level obtained in an oral glucose tolerance test (OGTT) during pregnancy.
This was after adjustment for age, prepregnancy BMI, previous gestational diabetes status, and number of weeks' gestation at the time of the oral glucose tolerance test, according to a paper published in Diabetes Care.
Objective: To compare efficiency of glucose challenge test with oral glucose tolerance test for detection of gestational diabetes mellitus (GDM).Methods: This observational cross sectional study was conducted in The Department of Obstetrics and Gynaecology Sharif Medical and Dental College / Sharif Medical City Hospital from December 2012 to June 2013.1000 consecutive pregnant ladies were included during this period between the gestational age group of 26 to30 weeks by using convenient sampling technique after analysis of risk factors.