optimal dose

op·ti·mal dose

(op'ti-măl dōs)
The dose of a drug or radiation that will produce the desired effect with minimum likelihood of undesirable symptoms.

op·ti·mal dose

(op'ti-măl dōs)
Dose of drug or radiation that will produce desired effect with least likelihood of undesirable symptoms.
References in periodicals archive ?
Kadmon expects to enroll an expansion cohort of approximately 40 patients after the optimal dose has been determined.
5 mg/kg body weight daily for the initial 5 days was considered as sub optimal dose for treatment of Bell's palsy in this study.
It is investigating three doses of Betalutin and different pre-dosing regimens, with the aim of identifying an optimal dose regimen to take into a pivotal Phase 2 PARADIGME trial.
The study will compare multiple doses of intravenous and subcutaneous dosing of DM199 to identify an optimal dose and delivery route for DM199 based on what is already known about urinary tissue kallikrein ("uKLK1"), trade name Kailikang.
While most of the panel agreed that the recommended dose had been shown to be clinically effective, they said that the optimal dose for treating ulcerative colitis (UC) had not yet been determined and that postapproval studies are needed to address optimal dosing, subpopulations of patients who may benefit most from treatment, and long-term safety.
Moreover, the subset of patients who received the optimal dose of WIG for the entire 3-year period had little to no decline in these measures from baseline, suggesting that clinical progression of the disease had been effectively halted.
The randomised, placebo-controlled trial is aimed at establishing the optimal dose and evaluating the safety of Cevira in patients with low- to moderate-grade CIN (CIN 1-2).
The trial is ongoing, and researchers will continue to study the optimal dose and monitor antitumor activity.
We need to determine the optimal dose of 2009 H1N1 influenza vaccine that can be safely administered to this at-risk population and whether one or two doses are needed to provide an immune response that is predictive of protection.
One group received their optimal dose of Vyvanse the first week and placebo the second week.
PICOLO was to identify the optimal dose for platelet inhibition in such patients.
However, the study was not a randomized trial, so the results do not definitively prove aspirin was responsible for the cuts in death rates, and because the reduction in deaths was the same for both doses of aspirin, there's no way to determine what the optimal dose is.

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