optical isomer


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optical isomer

n.
See enantiomer.
References in periodicals archive ?
Coupling GC with mass spectrometry has significantly enhanced the accuracy and reliability of measurements, but is still incapable of reliably distinguishing natural from synthetic ingredients, or molecules that are structural mirror images (optical isomers).
D-, L-, and D,L-tryptophan were used to estimate the ability of the [beta]-cyclodextrin bonded HEMA gel to separate the optical isomers. The sorbent particle size, the fraction particle size distribution, and the length of the spacer were found to influence the efficiency of the prepared columns.
Two other chemical groups are attached to this hexagon, but each can attach at two different angles, resulting in four different versions, or optical isomers. One of these has been found to be three to four times more effective than the original repellent at preventing yellow-fever-transmitting mosquitoes from biting.
"For example, we have separated alkaloids from plant extracts, purified synthetic peptides, and even separated optical isomers."
One particular type of analysis performed more easily and quickly by capillary electrophoresis is the separation of optical isomers. Using a micelle that will physically discriminate by preferential inclusion of one form relative to the other enables enantiomers to be separated.
Biologically active molecules frequently have optical isomers, and drug manufacturers need to know which form is present in their product formulations.
Considerable NMR work has been done over the past four years by Dawson, since joining the section, in structural characterization of new designer amphetamines as well as in the use of chiral shift reagents to differentiate between optical isomers of both ethical and illicit drugs while simultaneously obtaining molecular spectroscopic evidence to verify the authenticity of the examined substances.