optic neuropathy


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Related to optic neuropathy: optic neuritis, Ischemic optic neuropathy

optic neuropathy

Etymology: Gk, optikos, sight, neuron, nerve, pathos, disease
a disease, generally noninflammatory, of the eye, characterized by dysfunction or destruction of the optic nerve tissues. Causes include an interruption in the blood supply, compression by a tumor or aneurysm, a nutritional deficiency, and toxic effects of a chemical. The disorder, which can lead to blindness, usually affects only one eye.

optic neuropathy

Pathological injury to the optic nerves or the blood supply to them. Usually, only one eye is affected. Several forms have been described, including ischemic optic neuropathy, which, if prolonged, leads to blindness in the affected eye; optic neuritis due to acute demyelination of optic nerve fibers; infiltrative optic neuropathy, in which the optic nerve is compressed by a tumor or aneurysm; and optic neuropathy due to toxic nutritional factors, e.g., methanol or a combined nutritional and vitamin deficiency.
See also: neuropathy

neuropathy, optic

A non-inflammatory or degenerative disease of the optic nerve. See ophthalmopathy.
References in periodicals archive ?
Leber's Hereditary Optic Neuropathy (LHON) is a heritable genetic disease causing blindness.
Pomeranz and Lessell described a family in which there was a hereditary, probably autosomal recessive, chiasmal optic neuropathy in which all of the siblings had bitemporal visual field defects (9).
The other patient with dysthyroid optic neuropathy did not experience any improvement in visual acuity within 12 days of her first infusion, and so opted for an emergency orbital decompression.
24,25) Although demyelination is its most common identifiable cause, many other causes of optic neuropathy may resemble ON (see Table 2).
Ischemic optic neuropathy can be divided into anterior and posterior forms.
Seven years ago she suffered ischaemic optic neuropathy - a sudden loss of vision caused when blood vessels behind the eye are blocked following an operation.
The clinical and radiological features indicated an optic neuropathy, most likely ischaemic in aetiology The features of posterior ischaemic optic neuropathy and differential diagnosis are discussed
Stuart Carroll, who, with his uncle Les McGuinness of Canley, has Lebers hereditary optic neuropathy which has left him with 1/60th of his eyesight, said: "Treatment for our condition is only in its development stages, so it could be years before we can have our operations.
CONTEXT: Leber hereditary optic neuropathy (LHON) is a maternally inherited loss of central vision related to pathogenic mutations in the mitochondrial genome, which are a necessary but not sufficient condition to develop the disease.
Michael, who went blind last year from the rare condition Leber's Optic Neuropathy, said Tunstill saw him as an easy target.
Patients with severe GO can have sight loss with alteration in visual quality in one or more quadrants of the visual field (secondary to an optic neuropathy due to the compression of the optic nerve).