opsonization


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Related to opsonization: Complement system

opsonization

 [op″sŏ-nĭ-za´shun]
the rendering of bacteria and other cells subject to phagocytosis.

op·son·i·za·tion

(op'sŏn-ī-zā'shŭn),
The process by which bacteria and other cells are altered in such a manner that they are more readily and more efficiently engulfed by phagocytes.

op·son·i·za·tion

(op'sŏ-nī-zā'shŭn)
The process by which bacteria are altered so that they are more readily and more efficiently engulfed by phagocytes.
Synonym(s): opsonisation.

opsonization

The process by which bacteria or other antigen-bearing entities are rendered attractive to PHAGOCYTES by the binding of OPSONIN to their surface.
References in periodicals archive ?
For example, IgG1 can bind to C1q and activate the classical complement pathway opsonization, leading to phagocytosis of the S.
Opsonization: The process by which antibodies bind to a pathogen, thereby marking it for destruction by phagocytosis.
When poorly controlled, there is disturbance of cell-mediated immunity, alterations in opsonization and decreased chemotactic activity of granulocytes and monocytes.
Inhibition of complement-mediated opsonization and phagocytosis of Streptococcus pyogenes by D fragments of fibrinogen and fibrin bound to cell surface M protein.
Opsonization, biodistribution, cellular uptake and apoptosis study of PEGylated PBCA nanoparticle as potential drug delivery carrier.
It is responsible for debris scavenging, complement-mediated opsonization and lysis of foreign organisms, and bacterial destruction via oxidative burst mechanisms (i.e., superoxide and hydrogen peroxide formation).
PRRs, IgG, and IgM clusters recognize microbial or apoptotic cells and activate the complement cascade, which leads to the assembly of a terminal complement complex, bacterial lysis, and activation of several nonlethal signals that promote opsonization, chemotaxis, and TLR signaling [34] (Figure 2).
Soderhall, "Cell-mediated immunity in arthropods: hematopoiesis, coagulation, melanization and opsonization," Immunobiology, vol.
Artesunate induces changes either in the parasite or in the RBC directly and led to increased antigenicity and thus increased opsonization. Terminal half-lives of the orally administered drugs are usually less than 2 h.
This was due to the fact that phagocytosis is facilitated by antibody mediated opsonization. The communication between macrophages and B-cell is continuing through cytokine signaling as well as cell-cell contact involved in antigen presentation.
These cells are polymorphonuclear leukocytes which have capability to phagocyte the bare nuclei of other leukocytes with the help of auto antibodies, thus providing opsonization to the liberated nuclear material of the target cell.