Anne's; and in fifteen minutes I'll give you his opsonin
index in figures.
Purification and characterization of a humoral opsonin
from the solitary urochordate Syela clava.
Decreased rigidity due to the use of phospholipids with low melting temperature (Tm) for the preparation of liposomal formulation can lead to drug leakage and opsonin
However its endocytosis lacks cell-specificity and TaT peptide exposure at the liposome surface can lead to MPS elimination after opsonin
binding as well .
Matlak et al., "Galectin-3 functions as an opsonin
and enhances the macrophage clearance of apoptotic neutrophils," Glycobiology, vol.
The sea urchin complement homologue, SpC3, functions as an opsonin
protein-A Act as opsonin
and and -D macrophage activator.
Cisalpino et al., "PTX3 function as an opsonin
for the dectin-1-dependent internalization of zymosan by macrophages," Journal of Leukocyte Biology, vol.
Some products of complement activation are chemotactic to inflammatory cells (C5a), act as opsonins
(C3b), and can increase vascular permeability (C3a and C5a).
However, covalent binding method has been found to rule over the adsorption method since in vivo opsonins
may compete with the adsorbed molecules onto NP surface.
It is well known that following intravenous injection of radiolabeled magnetic nanoparticles in the bloodstream, plasma proteins, namely, opsonins
, are adsorbed onto the surface of the nanoparticles .
The presence of polyethylene glycol (PEG) on the surface of liposomes provides a steric barrier against opsonins
that reduces the uptake of liposomes by the MPS cells [13, 14] and thus allows their uptake by other cells.