opsonin


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Related to opsonin: opsonization, Cytokines

opsonin

 [op´sŏ-nin]
an antibody that renders bacteria and other cells susceptible to phagocytosis. adj., adj opson´ic.
immune opsonin an antibody that sensitizes a particulate antigen to phagocytosis.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

op·so·nin

(op'sŏ-nin),
Any blood serum protein that binds to antigens, enhancing phagocytosis (for example, C3b of the complement system, specific antibodies).
[G. opson, boiled meat, provisions, fr. hepsō, to boil, + -in]
Farlex Partner Medical Dictionary © Farlex 2012

opsonin

(ŏp′sə-nĭn)
n.
An antibody or product of complement activation in blood serum that causes bacteria or other foreign cells to become more susceptible to the action of phagocytes.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

op·so·nin

(op'sŏ-nin)
A substance that binds to antigens, enhancing phagocytosis.
[G. opson, boiled meat, provisions, fr. hepsō, to boil, + -in]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

opsonin

One of a number of substances, especially an antibody, naturally present in the blood that bind to the surface of bacteria to make them more readily susceptible to attack and destruction by PHAGOCYTES.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

opsonin

a type of ANTIBODY which binds to ANTIGENS, increasing their susceptibility to phagocytosis by other antibodies.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
Anne's; and in fifteen minutes I'll give you his opsonin index in figures.
Purification and characterization of a humoral opsonin from the solitary urochordate Syela clava.
Decreased rigidity due to the use of phospholipids with low melting temperature (Tm) for the preparation of liposomal formulation can lead to drug leakage and opsonin adsorption.
However its endocytosis lacks cell-specificity and TaT peptide exposure at the liposome surface can lead to MPS elimination after opsonin binding as well [317].
Matlak et al., "Galectin-3 functions as an opsonin and enhances the macrophage clearance of apoptotic neutrophils," Glycobiology, vol.
protein-A Act as opsonin and and -D macrophage activator.
Cisalpino et al., "PTX3 function as an opsonin for the dectin-1-dependent internalization of zymosan by macrophages," Journal of Leukocyte Biology, vol.
Some products of complement activation are chemotactic to inflammatory cells (C5a), act as opsonins (C3b), and can increase vascular permeability (C3a and C5a).
However, covalent binding method has been found to rule over the adsorption method since in vivo opsonins may compete with the adsorbed molecules onto NP surface.
It is well known that following intravenous injection of radiolabeled magnetic nanoparticles in the bloodstream, plasma proteins, namely, opsonins, are adsorbed onto the surface of the nanoparticles [46].
The presence of polyethylene glycol (PEG) on the surface of liposomes provides a steric barrier against opsonins that reduces the uptake of liposomes by the MPS cells [13, 14] and thus allows their uptake by other cells.