Reports of pain relief and improved mood following UVR exposure, withdrawal symptoms upon discontinuation of UVR, and the successful use of
opioid antagonists to reduce UVR dependence "underscore the importance of viewing tanning as a use disorder."
An emerging class of medications (
opioid antagonists) includes medications to target the exact mechanism of action that causes OIC.
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Opioid antagonists modified to prevent entry into the CNS (eg methylnaltrexone, naloxegol) are second-line remedies.
However, comfort levels are less secure with the safety of treatment with
opioid antagonists such as naltrexone, a nonselective opioid receptor antagonist that blocks the euphoric effects of opioids.
An increasing number of
opioid antagonists and other options are available for the treatment of OIC, generally supported by clinical trial evidence demonstrating their benefits and limitations for OIC.
SB15-053 increased access to
opioid antagonists to help combat overdoses.
The action of
opioid antagonists on alcohol consumption has played a decisive role in both the neurobiological understanding of alcohol addiction and in the pharmacological treatment of the disorder.
This legislation specifically permits licensed health care providers to prescribe
opioid antagonists, such as naloxone, to initial responders, as well as individuals at risk of experiencing an opiate overdose, their relatives, friends or caregivers.
Lightlake is focused on developing addiction treatments based on its expertise in
opioid antagonists.
"I think that's a really important finding and provides a new understanding of how
opioid antagonists work."
For example, some folks get relief from SSRIs, used to treat depression; gabapentin used to treat restless leg syndrome, seizures and nerve pain; pregabalin used to treat fibromyalgia and nerve pain; paroxetine used to treat obsessive compulsive disorder; and
opioid antagonists used to counter opiate overdoses.