opioid antagonists

o·pi·oid an·tag·o·nists

agents such as naloxone and naltrexone that have high affinity for opiate receptors but do not activate these receptors. These drugs block the effects of exogenously administered opioids such as morphine, heroin, meperidine, and methadone, or of endogenously released endorphins and enkephalins.

o·pi·oid an·tag·o·nists

(ōpē-oyd an-tagŏ-nists)
Agents with a high affinity for opiate receptors but do not activate them.
References in periodicals archive ?
Opioid antagonists have been considered for the treatment of kleptomania.
However, comfort levels are less secure with the safety of treatment with opioid antagonists such as naltrexone, a nonselective opioid receptor antagonist that blocks the euphoric effects of opioids.
MorphaBond is an abuse-deterrent formulation of extended release morphine using physical and chemical barriers, without the use of aversive agents or opioid antagonists.
An increasing number of opioid antagonists and other options are available for the treatment of OIC, generally supported by clinical trial evidence demonstrating their benefits and limitations for OIC.
SB15-053 increased access to opioid antagonists to help combat overdoses.
Opioid antagonists save lives by reversing the sedation and respiratory suppression commonly experienced during an opiate overdose with minimal risk of serious side effects.
Lightlake is focused on developing addiction treatments based on its expertise in opioid antagonists.
I think that's a really important finding and provides a new understanding of how opioid antagonists work.
methadone or buprenorphine), maintenance treatment with opioid antagonists (e.
It is decided to use opioid antagonists as rescue therapy for the management of the pruritus, and the patient is admitted in order to start treatment with naloxone, followed later on by naltrexone.
Maintenance treatment with depot opioid antagonists in subcutaneous implants: an alternative in the treatment of opioid dependence.
The most serious side effect of the opioid antagonists is respiratory depression, which is mediated by decreased sensitivity of the respiratory center to elevations in arterial carbon dioxide pressure (PaCO2).