open-lung biopsy

open-lung biopsy

An inpatient procedure in which lung tissue is obtained by a surgeon, usually via an intercostal incision, while the patient is under general anaesthesia.

Indications
Peripheral lung disease—e.g., interstitial pneumonia, suspected cancer.

Complications
Bleeding, 1–2%.
References in periodicals archive ?
In a group of patients with ARDS who underwent diagnostic open-lung biopsy, nine of 19 patients with a previous diagnosis of malignancy were found to have diffuse tumor infiltration of their lungs (four cases of leukemia and one case each of lymphoma, angiosarcoma, histiocytosis, adenocarcinoma and choriocarcinoma) (10).
Up to the present there has been only one case report of an open-lung biopsy showing slight thickening of the visceral pleura that was not apparent on the chest radiography (7).
A final cancer determination was made after several months of follow-up and, in some cases, open-lung biopsy.
However--thanks to some evidence in the literature suggesting the value of open-lung biopsy in acute respiratory distress syndrome, as well as the patients' severe condition--he performed broncho alveolar lavage.
To absolutely confirm the presence of bronchiolitis, an open-lung biopsy is required.
Bronchoscopy and open-lung biopsy revealed interstitial pneumonitis with lymphocytes and plasma cells.
Although, open-lung biopsy remains the standard for the diagnosis, but a good specimen obtained via transbronchial lung biopsy and TNB may be sufficient for making a diagnosis.
9) In addition, in a group of patients with ARDS who underwent diagnostic open-lung biopsy, (10) nine of 19 patient with a previous diagnosis of malignancy were found to have diffuse tumor infiltration of their lungs (four cases of leukemia and one case each of lymphoma, Angiosarcoma, Histiocytosis, Adenocarcinoma and Choriocarcinoma).
section] When sufficient clinical criteria for a definitive diagnosis of HP are lacking, lung biopsy may be indicated (9, 10); in addition, because transbronchial biopsy may sample unrepresentative areas of the lung, thoracoscopic or open-lung biopsy may be required.
25] If there is a clinical suspicion of PTLD and transbronchial biopsy is negative, open-lung biopsy is indicated.
Efforts to diagnose the pneumonia, which included bronchoalveolar lavage and transbronchial biopsy, were unsuccessful until an open-lung biopsy was performed.
The open-lung biopsy of the right upper lobe of the lung in 1997 revealed a diffuse lymphoid infiltrate that resembled the previous lung biopsy, but had greater architectural distortion, focal necrosis, and greater mitotic activity and cytologic atypia.