open-label trial


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open-label study

A clinical study in which the patients/subjects and investigators know which product each patient/subject is receiving, which is the opposite of a blinded study.

open-label trial

Clinical research A trial in which doctors and participants know which therapy is being administered. See Blinding.
References in periodicals archive ?
The open-label trial will enroll patients who have experienced a first myocardial infarction within the past three years and have evidence of left ventricular dysfunction.
The open-label trial which was carried out at four centers across the US2 involved 284 ECGs being performed on 29 patients with a history of mild-to-moderate asthma.
TURQUOISE II was an international, multicenter, randomized, open-label trial of 380 patients with Child-Pugh class A cirrhosis caused by HCV infection, explained Dr.
PROTECT VIII Kids is a multicenter, multinational, partially randomized, open-label trial evaluating the safety and efficacy of BAY 94-9027, at different dosing frequencies, in both prophylactic and on-demand treatment of bleeding in male children with severe hemophilia A.
A third post hoc analysis of the pooled phase III trial data and the 52-week open-label trial showed vilazodone had little effect on body weight and clinical laboratory measures.
Insulin sensitivity improved in patients on Yasmin alone or Yasmin plus metformin but significantly worsened with Yasmin plus cyproterone acetate in the open-label trial, Dr.
Seven hundred and seventy-three people completed the open-label trial, which concluded that Seditol provides relaxation, promotes restful sleep and helps reduce fatigue due to lack of sleep.
We are encouraged by the favorable results of this open-label trial, which make us even more eager to proceed at an even higher dose level in further clinical testing," stated CytRx's president and CEO Steven A.
The twelve-month, open-label trial demonstrated that NEXIUM effectively maintains basal acid output control in this patient population.
The Juvederm experience trial is a multi-center, open-label trial, designed to gain relevant information on physicians' use of Juvederm and Juvederm Ultra Plus and evaluate the persistence of and patient satisfaction with the products in daily clinical practice.
Investigators who studied this medication last year in a preliminary open-label trial in people with relapsing-remitting MS reported that it achieved a reduction in disease activity as measured by MRI.
This multicenter, randomized, controlled, open-label trial with blinded assessment of outcomes included 961 patients with acute deep-vein thrombosis.