open-angle glaucoma

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Related to open-angle glaucoma: Chronic open angle glaucoma

o·pen-·an·gle glau·co·ma

primary glaucoma in which the aqueous humor has free access to the trabecular meshwork.

open-angle glaucoma

See glaucoma.

o·pen-an·gle glau·co·ma

(ō'pĕn-ang'gĕl glaw-kō'mă)
This most prevalent form of the disease is sometimes called 'the thief in the night.' The flow of aqueous humor is slowed or completely stopped by an obstruction in the trabecular network.
Synonym(s): simple glaucoma, glaucoma simplex.

open-angle glaucoma

A condition in which the pressure of the fluid within the eye is increased to a damaging degree, but in which there is no apparent mechanical obstruction to the outflow of fluid through the normal drainage channel. This is the common type of GLAUCOMA, symptomless until a late stage and responsible for much avoidable blindness. Also known as chronic simple glaucoma.


a group of diseases of the eye characterized by increased intraocular pressure, resulting in pathological changes in the optic disk and typical visual field defects, and eventually blindness if not treated successfully. Uncommon in domestic animals, except in dogs where several breeds are predisposed.
The normal eye is filled with aqueous humor in an amount carefully regulated to maintain the shape of the eyeball. In glaucoma, the balance of this fluid is disturbed; fluid is formed more rapidly than it leaves the eye, and pressure builds up. The increased pressure damages the retina. If not relieved by proper treatment, the pressure will eventually damage the optic nerve, causing blindness.

absolute glaucoma
end-stage glaucoma with buphthalmos and severe degenerative changes.
aphakic glaucoma
forward displacement of the posterior lens capsule and vitreous body with incarceration in the pupil; usually occurs after cataract surgery.
closed-angle glaucoma
one in which the iridocorneal angle is obstructed, either due to collapse or interference with drainage by the iris or connective tissue. The cause may be congenital (goniodysgenesis) or acquired, due to an abnormality of the lens, anterior chamber or iris.
congenital glaucoma
that due to defective development of the structures in and around the anterior chamber of the eye, and resulting in impairment of drainage. See also goniodysgenesis.
narrow-angle glaucoma
a form of primary glaucoma caused by abnormal development of the iridocorneal angle. See also goniodysgenesis.
open-angle glaucoma
a form of glaucoma in which there is no detectable abnormality of the iridocorneal angle, but drainage is obstructed by elements in the aqueous humor, luxation of the lens, or elevated episcleral venous pressure. In some cases, particularly in predisposed breeds of dogs such as beagles, no contributing factors are detectable.
phacolytic glaucoma
leakage of lens material from a hypermature cataract causes anterior uveitis that impedes aqueous outflow.
primary glaucoma
increased intraocular pressure occurring in an eye with no other eye disease being present.
secondary glaucoma
increased intraocular pressure due to disease or injury to the eye.
References in periodicals archive ?
7 years of follow-up, 108 participants developed open-angle glaucoma.
Thus, when Rogers walked into the Iowa eye clinic during the summer of 1986 with his legal pad, the doctors took one look and realized they had stumbled upon the genetic equivalent of a winning lottery ticket: The family had enough living members with primary open-angle glaucoma to allow an intensive hunt for the flawed gene.
It also reviews key players involved in the therapeutic development for Open-Angle Glaucoma and special features on late-stage and discontinued projects.
If approved, this fixed-dose combination therapy will offer a simplified eye drop schedule and reduce the treatment burden for patients suffering from open-angle glaucoma or ocular hypertension.
MOORFIELDS EYE Hospital has partnered with medical laser company Lumenis for a project which seeks to establish Selective Laser Trabeculoplasty (SLT) technology as the new gold standard of care for open-angle glaucoma treatment.
Primary open-angle glaucoma (POAG) is the most prevalent form of glaucoma, accounting for approximately two-thirds of all diagnosed cases of glaucoma.
In fact, Harvard researchers say that about half of all normal-tension glaucoma patients and one-third of all primary open-angle glaucoma patients suffer from obstructive sleep apnea.
During a follow-up screening of these patients at Hopkins, ophthalmologists diagnosed the optic-nerve damage that characterizes primary open-angle glaucoma in 100 blacks and 32 whites.
Global Markets Direct's, 'Open-Angle Glaucoma - Pipeline Review, H1 2012', provides an overview of the Open-Angle Glaucoma therapeutic pipeline.
The authors report that patients whose retinal arteries had been the narrowest when the study began had an almost four-fold higher open-angle glaucoma (OAG) risk than those who had the widest arteries.
Its current product line includes the most prescribed treatment to lower elevated eye pressure in patients with ocular hypertension (abnormally high eye pressure) or open-angle glaucoma.
There are four basic forms of glaucoma; the most common, primary open-angle glaucoma, is the most difficult to recognize in its early stages.