oncostatin M

on·co·stat·in M

(ong'kō-stat'in), [MIM*165095]

A cytokine from macrophages, T cells, and some marrow and tumor cells, possessing various differentiation (in macrophages), cell proliferation (in hemopoietic precursors and some tumor types), and maturation (in fetal hepatocytes) effects.

[onco- + -stat + -in]

Farlex Partner Medical Dictionary © Farlex 2012

References in periodicals archive ?

Using a mouse infarct model, the Max Planck researchers succeeded in demonstrating that oncostatin M actually does stimulate the repair of damaged heart muscle tissue as presumed.

Whereas in the group in which oncostatin M could take effect almost all animals were still alive after four weeks, 40 percent of the genetically modified mice had died from the effects of the infarction," Braun said.

The reason for this was that oncostatin M ensured clearly quantifiable better cardiac function in the unmodified animals.

Scientists discover protein that controls heart cell regeneration

One of the two test groups had been modified genetically in advance to ensure that the oncostatin M could not have any effect in these animals.