Necrosis is usually defined as a process of cell collapse that involves oncosis
(increase in cell volume), rupture of plasma membrane and the unorganized dismantling of swollen organelles.
Morphological and biochemical aspects of apoptosis, oncosis
Vitamin K3 (menadione)-induced oncosis
associated with keratin 8 phosphorylation and histone H3 arylation.
is associated with exposure of phosphatidylserine residues on the outside layer of the plasma membrane: A reconsideration of the specificity of the annexin V/propidium iodide assay.
The glycotope-specific RAV12 monoclonal antibody induces oncosis
in vitro and has antitumor activity against gastrointestinal adenocarcinoma tumor xenografts in vivo.
3) Ultrastructural studies have indicated that the observed necrotic processes are a combination of apoptosis (active/ programmed cell death) and oncosis
(passive/accidental cell death).
Kahalalide F alters the function of the lysosomal membranes inducing cell death by oncosis
spun-off a new company, Cyntellect, to develop and commercialize the LEAP technology platform, which provides both high-throughput, multi-parameter cellular analysis as well as laser-based cellular manipulation .
Another form of cell death is in the process of reclaiming its maiden name, oncosis
Development of the technology is expected to lead to breakthroughs in cancer treatment, genomics, proteomics, gene therapy, drug discovery and transplantation, according to Oncosis
In contrast, the robust independent association of both cardiac troponin assays with LVMI suggests that prevalent ongoing subclinical myocyte cell death (in the form of oncosis
, apoptosis, or autophagy) is present among patients with stage 3-4 CKD.
6,642,018 for "Method for inducing a response in one or more targeted cells" is exclusively licensed by Cyntellect from Oncosis