oncoprotein


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Related to oncoprotein: Proto oncogenes

oncoprotein

A protein–eg, v-ras, encoded by an oncogene–eg, c-ras. See bcr-abl.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
E, Interestingly, the lymphatic tumor emboli (arrows) adjacent to that tumor are negative for HER2 oncoprotein expression (hematoxylin-eosin, original magnification X200 [A and B]; original magnification X200 [C through E]).
HPV16 oncoproteins induce MMPs/ RECK-TIMP-2 imbalance in primary keratinocytes: possible implications in cervical carcinogenesis.
Joshi et al., "MUC1-C oncoprotein functions as a direct activator of the nuclear factor-[kappa]B p65 transcription factor," Cancer Research, vol.
(2012) Structural insights into Helicobacter pylori oncoprotein CagA interaction with 01 integrin.
Hofler et al., "Post-translational control of IL-1[beta] via the human papillomavirus type 16 E6 oncoprotein: a novel mechanism of innate immune escape mediated by the E3-ubiquitin ligase E6-AP and p53," PLoS Pathogens, vol.
Dannenberg, "Cyclooxygenase2 transcription is regulated by human papillomavirus 16 E6 and E7 oncoproteins: evidence of a corepressor/coactivator exchange," Cancer Research, vol.
Molecular mechanisms of cervical carcinogenesis by high-risk human papillomaviruses: novel functions of E6 and E7 oncoproteins. Rev.
This is a retrospective study which evaluated all cases of invasive carcinoma of breast received in the UPR-School of Medicine Immunoperoxidase Laboratory, from 2008 to 2010, for which ER and PR hormonal receptors and HER-2 oncoprotein analysis were performed for clinical assessment.
The human epidermal growth factor receptor 2 (Her 2/ neu) or c-erbB-2 is an oncoprotein and belong to the Epidermal Growth Factor Receptor family4.
Previous studies suggest that p53 function is inactivated in cervical carcinoma either by complex formation with HPV-E6 viral oncoprotein product in HPV-positive cervical carcinoma leading to the degradation of wild-type p53 or rarely (1-6%) by gene mutation in HPV-negative cervical carcinoma [8, 19-20].
"The fused oncoprotein, because it directly regulates genes, leads to a series of further genetic changes in the cell," says Prof.
Tumors were evaluated for the expression of not only HPV but also a known biomarker of HPV oncoprotein function, the cyclin-dependent-kinase inhibitor p16, which is minimally detectable in HPV-negative tumors [35].