oncoprotein


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Related to oncoprotein: Proto oncogenes

oncoprotein

A protein–eg, v-ras, encoded by an oncogene–eg, c-ras. See bcr-abl.
References in periodicals archive ?
2014) Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.
The role of HPV E6 and E7 oncoproteins in HPV-associated cervical carcinogenesis.
Of the 717 cases, 230 cases were excluded from the study since they presented benign pathologic findings (n= 154), Ductal or Lobular Carcinoma In Situ (n= 54), or incomplete analysis of HER-2 oncoprotein (n=12).
Immunohistochemical analysis of the oncoprotein c-erb-B2 expression in oral benign and malignant lesions.
To develop a drug that would switch off Ras, scientists needed a binding site, an opening in the Ras oncoprotein to which the docking mechanism of a therapeutic molecule could attach.
The Myc oncoprotein as a therapeutic target for human cancer.
Human papillomavirus type 16 E7 oncoprotein can induce abnormal centrosome duplication through a mechanism independent of inactivation of retinoblastoma protein family members.
The p16INK4a appeared as overexpressed by the interaction of high-risk HPV E7 oncoprotein and the pRb, resulting in the release of the E2F transcription factor.
MGAH22, an Fc-modified monoclonal antibody, targets the HER2 oncoprotein, which is overexpressed on the surface of various cancer cells and plays an important role in tumorigenesis, tumor aggressiveness, and outcome in breast and other cancers.
Some specific topics reported here include mimics of growth factors and cytokines, and peptide aptamers targeting the viral E6 oncoprotein.