oncoprotein


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Related to oncoprotein: Proto oncogenes

oncoprotein

A protein–eg, v-ras, encoded by an oncogene–eg, c-ras. See bcr-abl.
References in periodicals archive ?
In the presence of HR-HPV, virally encoded oncoproteins E6 and E7 can form specific complexes with tumor suppressor gene products.
4) The HPV E6 and E7 early genes encode oncoproteins responsible for cervical neoplastic transformation (3) by inactivating tumour suppressors as well as promoting the accumulation of genetic mutations.
To develop a drug that would switch off Ras, scientists needed a binding site, an opening in the Ras oncoprotein to which the docking mechanism of a therapeutic molecule could attach.
Thus, therapies are needed for patients whose tumors overexpress the HER2 oncoprotein at lower levels without gene amplification.
Correlation between serological immune response analyzed by a new ELISA for HPV-16/18 E7 oncoprotein and clinical characteristics of cervical cancer patients.
Muller S, Miller WH, Dejean A, Trivalent antimonals induce degradation of the PML-RARa oncoprotein and reorganization of the promyelocytic leukemia nuclear bodies in acute promyelocytic leukemia NB4 cells.
Announced today, the Phase II Small Business Innovation Research (SBIR) grant will fund the company's test based on detection of the HPV-E6 oncoprotein.
Mutations in the KIT receptor tyrosine kinase give rise to the critical transforming oncoprotein in 85% of gastrointestinal stromal tumors (GISTs).
There was also focal positive immunoreactivity for Ras-10 oncoprotein.
Colby Pharmaceutical Company (Colby), a private San Jose, CA biopharmaceutical company, announced that it received a National Cancer Institute (NCI) SBIR funding award for small molecule inhibitors of interactions between Androgen Receptor (AR) Protein with JunD Oncoprotein for treatment of prostate cancer (PCa).
which commercializes E6 and E7 oncoprotein immunoassays for HPV-related cancers.
This protein, called c-MYC oncoprotein, can initiate and promote almost all human cancers and discovering the role it plays in cancer treatment resistance may lead to advances that save lives.