oncoprotein

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Related to oncoprotein: Proto oncogenes

oncoprotein

A protein–eg, v-ras, encoded by an oncogene–eg, c-ras. See bcr-abl.

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References in periodicals archive ?

2014) Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.

Structure and function of helicobacter pylori CagA, the first-identified bacterial protein involved in human cancer

The role of HPV E6 and E7 oncoproteins in HPV-associated cervical carcinogenesis.

Frequency of E6 and E7 Oncogenes of Human Papillomavirus Types 16 and 18 in Cervical Cancer Patients in Pakistani Women

Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein.

Epigenetic Silencing of Eyes Absent 4 Gene by Acute Myeloid Leukemia 1-Eight-twenty-one Oncoprotein Contributes to Leukemogenesis in t(8;21) Acute Myeloid Leukemia

Of the 717 cases, 230 cases were excluded from the study since they presented benign pathologic findings (n= 154), Ductal or Lobular Carcinoma In Situ (n= 54), or incomplete analysis of HER-2 oncoprotein (n=12).

Expression of basal-like biomarkers in triple negative invasive breast carcinoma in Puerto Rico

Human papillomavirus E6 and E7 oncoproteins as risk factors for tumorigenesis.

Revealing highly conserved regions in the E6 protein among distinct human papillomavirus types using comparative analysis of multiple sequence alignments

Immunohistochemical analysis of the oncoprotein c-erb-B2 expression in oral benign and malignant lesions.

Coexpression of p53 and Ki 67 and lack of c-erbB2 expression in oral leukoplakias in India

To develop a drug that would switch off Ras, scientists needed a binding site, an opening in the Ras oncoprotein to which the docking mechanism of a therapeutic molecule could attach.

Binding pocket of 'functional significance' in cancer causing gene uncovered

The Myc oncoprotein as a therapeutic target for human cancer.

Alteraciones del gen c-Myc en la oncogenesis

Human papillomavirus type 16 E7 oncoprotein can induce abnormal centrosome duplication through a mechanism independent of inactivation of retinoblastoma protein family members.

Infeccion por el VPH y la carcinogenesis en el tracto aero-digestivo superior

The p16INK4a appeared as overexpressed by the interaction of high-risk HPV E7 oncoprotein and the pRb, resulting in the release of the E2F transcription factor.

Chlamydia trachomatis and human papillomavirus coinfection: association with p16INK4a and Ki67 expression in biopsies of patients with pre-neoplastic and neoplastic lesions

MGAH22, an Fc-modified monoclonal antibody, targets the HER2 oncoprotein, which is overexpressed on the surface of various cancer cells and plays an important role in tumorigenesis, tumor aggressiveness, and outcome in breast and other cancers.

MACROGENICS BEGINS PHASE I CLINICAL TRIAL OF MGAH22

Some specific topics reported here include mimics of growth factors and cytokines, and peptide aptamers targeting the viral E6 oncoprotein.