The relationship of many of these miRNAs with their target genes is unknown, but miR-19 is necessary for inhibition of apoptosis and oncogenesis
in lymphocytes (Olive et al., 2009).
Gene fusions can also induce oncogenesis
without producing a novel protein.
Ness, "Situational awareness: regulation of the myb transcription factor in differentiation, the cell cycle and oncogenesis
," Cancers, vol.
Segun algunas investigaciones, la mayor ingesta de grasa estaria relacionada con dos mecanismos que podrian colaborar con la oncogenesis
del CCR; alteracion en la senalizacion de la insulina a nivel de AKT y una estimulacion de la proliferacion de celulas colonicas promovidas por la ruta quinasa c-Jun N-terminal (JNK) en el epitelio colonico (39).
The different social histories between male and female patients casts doubt on some of the traditional theories about oncogenesis
Recent advances have contributed largely to our knowledge of HPV oncogenesis
and how it causes cervical cancer, so much so, that persistent HPV infections can be detected using new technologies now and are been used for managing persons who are infected.
They arise from epithelium enriched with the potentiality of oncogenesis
. There are many variants of ameloblastomas, but the cell type tends to mimic the ameloblast.
The exact mode of oncogenesis
is not known but is related to controlling cell cycle progression, cellular migration and proliferation, and most importantly evasion from apoptosis and host immune system9.
Isocitrate dehydrogenase mutations in chondrosarcoma: the crossroads between cellular metabolism and oncogenesis
. Curr Opin Oncol 2014;26(4):403-407.
Stivarga is an oral inhibitor of multiple kinases involved in normal cellular functioning and in pathological processes, including oncogenesis
, tumor angiogenesis, metastasis and tumor immunity.
Investigation of a new SHP2 substrate(s) potentially involved in CagA-mediated oncogenesis
revealed parafibromin/Cdc73, a core component of the RNA polymerase II-associated factor (PAF) complex.
This review consolidates the current evidence for the role NTS and its receptors play in the oncogenesis
of CRC and identifies areas of translational research required to allow NTS to be used in the diagnosis and treatment of this prevalent cancer.