Parotid gland oncocytosis
: CT findings with histopathologic correlation.
Emerging entities in renal cell neoplasia: thyroid-like follicular renal cell carcinoma and multifocal oncocytoma-like tumours associated with oncocytosis
The World Health Organization (2005) classified oncocytic lesions into three distinct categories of oncocytosis
, oncocytoma, and oncocytic carcinoma.
Butter, "Renal oncocytosis
in a pediatric patient: Case report and review of the literature," Journal of Pediatric Surgery Case Reports, vol.
Harawi, "Oncocytes, oncocytosis
, and oncocytic tumors," Pathology Annual, vol.
Hybrid oncocytoma/chromophobe tumour/renal cell carcinoma is rare kidney tumour, which can be associated with renal oncocytosis
and Birt-Hogg-Dube syndrome; rare sporadic HOCT were also described.
A case of acquired renal cystic disease (ACDK) with oncocytosis
, a dominant nodule (oncocytoma), multiple adenomas and a microscopic papillary renal cell carcinoma associated with crescentic glomerulonephritis.
In this regard, Brandwein and Huvos (1) found a history of radiation exposure in some of their cases, and Becker et al (14) described an age-dependent intracellular metabolic defect associated with mitochon driopathy as an explanation for the development of oncocytosis
in 2 of their cases.
(26,27) This syndrome can manifest with multifocal oncocytomas (oncocytosis
) and chRCC and should be suggested by a pathologist when more than one lesion is present unilaterally or bilaterally.
The occurrence of oncocytic cells in salivary glands can be categorized as oncocytic metaplasia, nodular or diffuse oncocytosis
, and oncocytoma.
(1) These tumors are classified as one of three types: diffuse oncocytosis
, focal adenomatous oncocvtic hyperplasia, and oncocytoma.
In the first large series on hybrid tumors, Tickoo et al (13) reported on a group of patients with renal oncocytosis
, some of whom developed tumors with hybrid morphologies.