oncocytoma


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on·co·cy·to·ma

(ong'kō-sī-tō'mă), [MIM*553000]
A glandular tumor composed of large cells with cytoplasm that is granular and eosinophilic because of the presence of abundant mitochondria; occurs uncommonly in the kidney, salivary glands, and endocrine glands.
Synonym(s): oxyphil adenoma
[onco- + G. kytos, cell, + -oma, tumor]

oncocytoma

/on·co·cy·to·ma/ (ong″ko-si-to´mah)
1. a usually benign adenoma composed of oncocytes with granular, eosinophilic cytoplasm.
2. a benign Hürthle cell tumor.

renal oncocytoma  a benign neoplasm of the kidney resembling a renal cell carcinoma but encapsulated and not invasive.

oncocytoma

A usually benign tumor characterized by aggregates of bland pink cells Locations Bronchial, lacrimal, salivary, parathyroid, and thyroid glands–Hürthle cell adenoma, anterior pituitary, kidney; rarely, malignant oncocytomas occur in salivary glands, nasal cavity, paranasal sinuses, mediastinum and thyroid and kidneys DiffDx Oncocytic CA of pancreas, oncocytic carcinoid of lungs, clinically similar to 'garden variety' carcinoid, oncocytosis of salivary gland, an age-related hyperplasia

on·co·cy·to·ma

(ong'kō-sī-tō'mă) [MIM*553000]
A glandular tumor composed of large cells with cytoplasm that is granular and eosinophilic because of the presence of abundant mitochondria; occurs uncommonly in the kidney and salivary and endocrine glands.

oncocytoma (ong´kōsītō´mə),

n a rare, benign tumor usually occurring in the parotid glands in older patients. The lesion is encapsulated and composed of sheets and cords of large eosinophilic cells with small nuclei. Also called
acidophilic adenoma, oxyphilic adenoma.
Enlarge picture
Oncocytoma.

oncocytoma

a rare benign neoplasm arising from oncocytes.
References in periodicals archive ?
A classic oncocytoma has a central hyalinized or edematous scar with rounded nests of tumor cells; toward the periphery of the tumor these nests can be back to back, imparting a more solid growth pattern.
Like renal oncocytomas, they are not innocuous, however, as they can continue to grow and disrupt the surrounding kidney tissue.
The tumour is characterised by large cells with abundant granular to fluffy cytoplasm with well-defined cell borders and perinuclear clearing (1-9) leading to confusion with clear cell carcinoma and oncocytoma.
61%) each of haemangioma, basal cell adenoma, oncocytoma, myoepithelioma and sebaceous lymphadenoma (Table 1 and Table 3).
1 (a-d) shows the lesion identified at original scan and provisionally diagnosed as an oncocytoma.
Oncocytoma is a rare benign tumour of the salivary gland accounting for 1% of all benign salivary gland tumours.
Hereditary and Non-Hereditary Rick Factors Hereditary Risk Factors Tuberous sclerosis, von Hippel-Lindau gene, heredi- tary papillary renal cell carci- noma, hereditary leiomyoma --renal cell carcinoma, Birt- Hogg-Dube syndrome, hereditary renal oncocytoma Non-Hereditary Risk Factors Tobacco, obesity, male, African American, hyperten sion, phenacetin, acquired cystic disease, workplace exposures (such as asbestos, benzene, trichloroethylene) Source: American Cancer Society, 2011.
Many renal tumors may exhibit some degree of cytoplasmic eosinophilia; these tumors include eosinophilic/ granular variant of clear cell RCC, papillary RCC type 2, eosinophilic variant of chromophobe RCC, renal oncocytoma, and epithelioid AML.
Pituicytoma, spindle cell oncocytoma, and granular cell tumor: Clarification and meta-analysis of the world literature since 1893.
Interestingly, another study exploring the activity of CB1 receptors in chromophobe and renal oncocytoma tissue lines found that they were expressed in similar levels to that of non-tumour tissues.
There were two false positives, which came out to be inflammatory mass in one and oncocytoma in the other.