oncocytoma


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on·co·cy·to·ma

(ong'kō-sī-tō'mă), [MIM*553000]
A glandular tumor composed of large cells with cytoplasm that is granular and eosinophilic because of the presence of abundant mitochondria; occurs uncommonly in the kidney, salivary glands, and endocrine glands.
Synonym(s): oxyphil adenoma
[onco- + G. kytos, cell, + -oma, tumor]

oncocytoma

A usually benign tumor characterized by aggregates of bland pink cells Locations Bronchial, lacrimal, salivary, parathyroid, and thyroid glands–Hürthle cell adenoma, anterior pituitary, kidney; rarely, malignant oncocytomas occur in salivary glands, nasal cavity, paranasal sinuses, mediastinum and thyroid and kidneys DiffDx Oncocytic CA of pancreas, oncocytic carcinoid of lungs, clinically similar to 'garden variety' carcinoid, oncocytosis of salivary gland, an age-related hyperplasia

on·co·cy·to·ma

(ong'kō-sī-tō'mă) [MIM*553000]
A glandular tumor composed of large cells with cytoplasm that is granular and eosinophilic because of the presence of abundant mitochondria; occurs uncommonly in the kidney and salivary and endocrine glands.
References in periodicals archive ?
GHG in granular cell carcinoma, chromophobe cell carcinoma, oncocytoma of the kidney.
Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma. Human molekuler genetics 2008; 1;17:986-995.
In this study, we investigated the MRI features of renal tumors, namely T2 signal intensities, T2 signal intensity ratios, enhancement patterns, and enhancement ratios that might allow differentiation of oncocytoma from chromophobe RCC.
The World Health Organization (2005) classified oncocytic lesions into three distinct categories of oncocytosis, oncocytoma, and oncocytic carcinoma.
Rashid et al., "Active surveillance is suitable for intermediate term follow-up of renal oncocytoma diagnosed by percutaneous core biopsy," BJU International, vol.
Differential diagnoses included primary clear cell carcinoma of the parotid gland, metastatic disease of the thyroid gland and the kidney including subtypes (clear cell carcinoma, papillary carcinoma, and chromophobe carcinoma), renal cell adenoma, lymphoma, sarcoma, oncocytoma, and mesenchymal tumours like schwannoma and angioleiomyoma.
We herein describe the case of a 61-year-old male who suffered from right parotid oncocytoma with facial nerve paralysis.
However, there are few reported cases of BHD with parotid gland oncocytoma. Here we present a rare case of a patient with this association.
A similar situation, with a seemingly benign tumor involving the renal vein, has been reported in rare cases of renal oncocytoma. Renal oncocytomas with intravascular extension into the renal vein [36] did not show morphologic, immunohistochemical, or cytogenetic differences from their counterparts without evidence of intravascular invasion.
She eventually underwent resection of the left kidney mass with a partial nephrectomy and a final pathologic diagnosis of an oncocytoma, which is a typical tumor type for Birt-Hogg-Dube syndrome.
Renal oncocytoma was first described by Zippel in 1942 as a malignant entity [1].
The routine histologic diagnosis of a renal oncocytoma is exclusively based on morphologic criteria such as the presence of large epithelial cells in small groups with irregular nuclei and finely granular acidophilic cytoplasm [1].