omeprazole


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Related to omeprazole: ranitidine, Losec

omeprazole

 [o-mep´ra-zōl]
a proton pump inhibitor, used in treatment of dyspepsia, gastroesophageal reflux disease, disorders of gastric hypersecretion, and peptic ulcer, including that associated with Helicobacter pylori infection; administered orally.

omeprazole

(ō-mĕp′rə-zōl′)
n.
A proton pump inhibitor drug, C17H19N3O3S, that suppresses gastric acid secretion and is used for the treatment of duodenal and gastric ulcers and gastroesophageal reflux disease.

omeprazole

Prilosec® Therapeutics A proton pump inhibitor used to manage GERD; heartburn; erosive esophagitis; maintenance of healed erosive esophagitis; short-term management of active duodenal ulcer and active benign gastric ulcer, and for certain hypersecretory conditions; combined with clarithromycin to eradicate H pylori associated with duodenal ulcers. See GERD, Helicobacter pylori. Cf H2 blockers.

omeprazole

The first of the class of proton pump inhibitor drugs used to control the production of stomach acid and treat stomach and duodenal ulcers and especially the ZOLLINGER-ELLISON SYNDROME. OMEPRAZOLE can be effective in cases that have failed to respond to H-2 receptor blocker drugs such as RANITIDINE. The drug is long-acting and need only be taken once a day. A brand name is Losec.
References in periodicals archive ?
The combined market of Prilosec OTC and private label omeprazole OTC products had US retail sales of approximately USD 492m for the most recent twelve months ending in October 2018 according to IRI.
Omeprazole (4.0 mg/kg), the positive control drug, demonstrated a potency for reducing the gastric ulcer index (15.35 [+ or -] 1.22 [mm.sup.2]; P <0.001 compared to the model group).
A month later, when the patient was asymptomatic, he returned to the pharmaceutical company, being switched from his previous job to the reactor manufacturing omeprazole. A few days after that, he presented erythematous eruptions involving face and neck with itching.
Omeprazole as a kind of white crystalline powder can reduce the activity of H+, K+ and APT enzyme, inhibit the secretion of gastric acid and prevent bacterial infection by acting on gastric mucosal wall cells directly.
73% of patients were relieved of epigastric pain at the end of 2 weeks in rabeprazole group in comparison to 48% and 65% in omeprazole and lansoprazole groups, respectively.
MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) tetrazolium reduction assays were performed to evaluate the survival of cells in the presence of omeprazole and esomeprazole Different concentrations of omeprazole and esomeprazole were used to determine the exact drug concentration that could allow 80%-90% cell survival.
Omeprazole salts were prepared from the omeprazole purchased from Shouguang Fukang Pharmaceutical.
Compound Retention Plates Resolution RRT Time (min) 1 Omeprazole 7.46 11978 -- 0.85 Related Substance A 2 Omeprazole 8.69 12271 4.2 1.00 Figure 1B: Esomeprazole Magnesium (API assay).
The PDA-approved facilities in Fontaine and Pessac will manufacture the Omeprazole mini-tablets, while in Strangnas the final product will be encapsulated and packaged ready for final release.
PPIs such as omeprazole (Prilosec[R]) are, to a minor degree, broken down by the same liver enzyme which metabolizes warfarin.
Following a failed test, the punishment was inevitable under the rules, but there will be sympathy for the Godolphin trainer among colleagues who maintain that products containing omeprazole are widely used to treat ulcers, a common condition for racehorses, and that it is not performance-enhancing.
ABSTRACT Objective: The objective of this study was to evaluate and compare the effectiveness of single dose of omeprazole 20mg and esomeprazole 40mg on stomach pH.Material and Methods: In this study 50 patients of ASA class p1 and p2 status of age 15 to 60 years and body mass index (BMI) 20 to 35 kg/m2 undergoing inguinal hernia surgery electively of both sexes were included.