olsalazine


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Related to olsalazine: Olsalazine sodium, Balsalazide, Dipentum

olsalazine

 [ol-sal´ah-zēn]
a derivative of mesalamine used as the sodium salt as an antiinflammatory in ulcerative colitis.

olsalazine

/ol·sal·a·zine/ (ol-sal´ah-zēn) a derivative of mesalamine used as the sodium salt as an antiinflammatory in ulcerative colitis.

olsalazine

A salicylate drug used to treat ulcerative colitis. A brand name is Dipentum.

olsalazine

5-amino-salicylate; used in the treatment of ulcerative colitis.
References in periodicals archive ?
Two other agents in this class, balsalazide (Colazal) and olsalazine (Dipentum), are broken down in the colon to 5-ASA.
Three medicines are used for treating an acute attack: Aminosalicylates (such as balsalazide, mesalazine, olsalazine, sulfasalazine), Corticosteroids (budesonide, hydrocortisone, prednisolone) and Immunosuppressants (azathioprine, ciclosporin, mercaptopurine) Rest is important during an attack to allow healing to take place.
Olsalazine and 6-mercaptopurine-related bone marrow suppression: a possible drug-drug interaction.
Active UC should be treated initially with systemic aminosalicylate drugs (such as sulfasalazine, olsalazine, balsalazide, and mesalamine) or with corticosteroids.
In vitro kinetic studies with recombinant human TPMT demonstrated that sulfasalazine, 5-aminosalicylic acid, balsalazide, and olsalazine (3-5) inhibit the enzyme activity in a noncompetitive manner.