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Medical dictionaries define oligomenorrhea as infrequent or very light menstruation. But physicians typically apply a narrower definition, restricting the diagnosis of oligomenorrhea to women whose periods were regularly established before they developed problems with infrequent flow. With oligomenorrhea, menstrual periods occur at intervals of greater than 35 days, with only four to nine periods in a year.


True oligomenorrhea can not occur until menstrual periods have been established. In the United States, 97.5% of women have begun normal menstrual cycles by age 16. The complete absence of menstruation, whether menstrual periods never start or whether they stop after having been established, is called amenorrhea. Oligomenorrhea can become amenorrhea if menstruation stops for six months or more.
It is quite common for women at the beginning and end of their reproductive lives to miss or have irregular periods. This is normal and is usually the result of imperfect coordination between the hypothalamus, the pituitary gland, and the ovaries. For no apparent reason, a few women menstruate (with ovulation occurring) on a regular schedule as infrequently as once every two months. For them that schedule is normal and not a cause for concern.
Women with polycystic ovary syndrome (PCOS) are also likely to suffer from oligomenorrhea. PCOS is a condition in which the ovaries become filled with small cysts. Women with PCOS show menstrual irregularities that range from oligomenorrhea and amenorrhea on the one hand to very heavy, irregular periods on the other. The condition affects about 6% of premenopausal women and is related to excess androgen production.
Other physical and emotional factors also cause a woman to miss periods. These include:
  • emotional stress
  • chronic illness
  • poor nutrition
  • eating disorders such as anorexia nervosa
  • excessive exercise
  • estrogen-secreting tumors
  • illicit use of anabolic steriod drugs to enhance athletic performance
Professional ballet dancers, gymnasts, and ice skaters are especially at risk for oligomenorrhea because they combine strenuous physical activity with a diet intended to keep their weight down. Menstrual irregularities are now known to be one of the three disorders comprising the so-called "female athlete triad," the other disorders being disordered eating and osteoporosis. The triad was first formally named at the annual meeting of the American College of Sports Medicine in 1993, but doctors were aware of the combination of bone mineral loss, stress fractures, eating disorders, and participation in women's sports for several decades before the triad was named. Women's coaches have become increasingly aware of the problem since the early 1990s, and are encouraging female athletes to seek medical advice.

Causes and symptoms

Symptoms of oligomenorrhea include:
  • menstrual periods at intervals of more than 35 days
  • irregular menstrual periods with unpredictable flow
  • some women with oligomenorrhea may have difficulty conceiving.
Oligomenorrhea that occurs in adolescents is often caused by immaturity or lack of synchronization between the hypothalamus, pituitary gland, and ovaries. The hypothalamus is part of the brain that controls body temperature, cellular metabolism, and basic functions such as eating, sleeping, and reproduction. It secretes hormones that regulate the pituitary gland.
The pituitary gland is then stimulated to produce hormones that affect growth and reproduction. At the beginning and end of a woman's reproductive life, some of these hormone messages may not be synchronized, causing menstrual irregularities.
In PCOS, oligomenorrhea is probably caused by inappropriate levels of both female and male hormones. Male hormones are produced in small quantities by all women, but in women with PCOS, levels of male hormone (androgens) are slightly higher than in other women. More recently, however, some researchers are hypothesizing that the ovaries of women with PCOS are abnormal in other respects. In 2003, a group of researchers in London reported that there are fundamental differences between the development of egg follicles in normal ovaries and follicle development in the ovaries of women with PCOS.
In athletes, models, actresses, dancers, and women with anorexia nervosa, oligomenorrhea occurs because the ratio of body fat to weight drops too low.


History and physical examination

Diagnosis of oligomenorrhea begins with the patient informing the doctor about infrequent periods. The doctor will ask for a detailed description of the problem and take a history of how long it has existed and any patterns the patient has observed. A woman can assist the doctor in diagnosing the cause of oligomenorrhea by keeping a record of the time, frequency, length, and quantity of bleeding. She should also tell the doctor about any recent illnesses, including longstanding conditions like diabetes mellitus. The doctor may also inquire about the patient's diet, exercise patterns, sexual activity, contraceptive use, current medications, or past surgical procedures.
The doctor will then perform a physical examination to evaluate the patient's weight in proportion to her height, to check for signs of normal sexual development, to make sure the heart rhythm and other vital signs are normal, and to palpate (feel) the thyroid gland for evidence of swelling.
In the case of female athletes, the doctor may need to establish a relationship of trust with the patient before asking about such matters as diet, practice and workout schedules, and the use of such drugs as steroids or ephedrine. The presence of stress fractures in young women should be investigated. In some cases, the doctor may give the patients the Eating Disorder Inventory (EDI) or a similar screening questionnaire to help determine whether the patient is at risk for developing anorexia or bulimia.

Laboratory tests

After taking the woman's history, the gynecologist or family practitioner does a pelvic examination and Pap test. To rule out specific causes of oligomenorrhea, the doctor may also do a pregnancy test and blood tests to check the level of thyroid hormone. Based on the initial test results, the doctor may want to do tests to determine the level of other hormones that play a role in reproduction.
As of 2003, more sensitive monoclonal assays have been developed for measuring hormone levels in the blood serum of women with PCOS, thus allowing earlier and more accurate diagnosis.

Imaging studies

In some cases the doctor may order an ultrasound study of the pelvic region to check for anatomical abnormalities, or x rays or a bone scan to check for bone fractures. In a few cases the doctor may order an MRI to rule out tumors affecting the hypothalamus or pituitary gland.


Treatment of oligomenorrhea depends on the cause. In adolescents and women near menopause, oligomenorrhea usually needs no treatment. For some athletes, changes in training routines and eating habits may be enough to return the woman to a regular menstrual cycle.
Most patients suffering from oligomenorrhea are treated with birth control pills. Other women, including those with PCOS, are treated with hormones. Prescribed hormones depend on which particular hormones are deficient or out of balance. When oligomenorrhea is associated with an eating disorder or the female athlete triad, the underlying condition must be treated. Consultation with a psychiatrist and nutritionist is usually necessary to manage an eating disorder. Female athletes may require physical therapy or rehabilitation as well.

Alternative treatment

As with conventional medicial treatments, alternative treatments are based on the cause of the condition. If a hormonal imbalance is revealed by laboratory testing, hormone replacements that are more "natural" for the body (including tri-estrogen and natural progesterone) are recommended. Glandular therapy can assist in bringing about a balance in the glands involved in the reproductive cycle, including the hypothalmus, pituitary, thyroid, ovarian, and adrenal glands. Since homeopathy and acupuncture work on deep, energetic levels to rebalance the body, these two modalities may be helpful in treating oligomenorrhea. Western and Chinese herbal medicines also can be very effective. Herbs used to treat oligomenorrhea include dong quai (Angelica sinensis), black cohosh (Cimicifuga racemosa), and chaste tree (Vitex agnus-castus). Herbal preparations used to bring on the menstrual period are known as emmenagogues. For some women, meditation, guided imagery, and visualization can play a key role in the treatment of oligomenorrhea by relieving emotional stress.
Diet and adequate nutrition, including adequate protein, essential fatty acids, whole grains, and fresh fruits and vegetables, are important for every woman, especially if deficiencies are present or if she regularly exercises very strenuously. Female athletes at the high school or college level should consult a nutritionist to make sure that they are eating a well-balanced diet that is adequate to maintain a healthy weight for their height. Girls participating in dance or in sports that emphasize weight control or a slender body type (gymnastics, track and field, swimming, and cheerleading) are at higher risk of developing eating disorders than those that are involved in such sports as softball, weight lifting, or basketball. In some cases the athlete may be given calcium or vitamin D supplements to lower the risk of osteoporosis.
Many women, including those with PCOS, are successfully treated with hormones for oligomenorrhea. They have more frequent periods and begin ovulating during their menstrual cycle, restoring their fertility.
For women who do not respond to hormones or who continue to have an underlying condition that causes oligomenorrhea, the outlook is less positive. Women who have oligomenorrhea may have difficulty conceiving children and may receive fertility drugs. The absence of adequate estrogen increases risk for bone loss (osteoporosis) and cardiovascular disease. Women who do not have regular periods also are more likely to develop uterine cancer. Oligomenorrhea can become amenorrhea at any time, increasing the chance of having these complications.


Oligomenorrhea is preventable only in women whose low body fat to weight ratio is keeping them from maintaining a regular menstrual cycle. Adequate nutrition and a less vigorous training schedules will normally prevent oligomenorrhea. When oligomenorrhea is caused by hormonal factors, it is not preventable, but it is often treatable.

Key terms

Anorexia nervosa — A disorder of the mind and body in which people starve themselves in a desire to be thin, despite being of normal or below normal body weight for their size and age.
Cyst — An abnormal sac containing fluid or semisolid material.
Emmenagogue — A medication or herbal preparation given to bring on a woman's menstrual period.
Female athlete triad — A combination of disorders frequently found in female athletes that includes disordered eating, osteoporosis, and oligo- or amenorrhea. The triad was first officially named in 1993.
Osteoporosis — The excessive loss of calcium from the bones, causing the bones to become fragile and break easily. Women who are not menstruating are especially vulnerable to this condition because estrogen, a hormone that protects bones against calcium loss, decreases drastically after menopause.



American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th ed., revised. Washington, D.C.: American Psychiatric Association, 2000.
Beers, Mark H., MD, and Robert Berkow, MD, editors. "Menstrual Abnormalities and Abnormal Uterine Bleeding." Section 18, Chapter 235 In The Merck Manual of Diagnosis and Therapy. Whitehouse Station, NJ: Merck Research Laboratories, 2004.
Pelletier, Kenneth R., MD. The Best Alternative Medicine, Part II, "CAM Therapies for Specific Conditions: Menstrual Symptoms, Menopause, and PMS." New York: Simon & Schuster, 2002.


Barrow, Boone, MD. "Female Athlete Triad." eMedicine June 17, 2004. http://www.emedicine.com/sports/topic163.htm.
Chandran, Latha, MBBS, MPH. "Menstruation Disorders." eMedicine August 9, 2004. http://www.emedicine.com/ped/topic2781.htm.
Hopkinson, R. A., and J. Lock. "Athletics, Perfectionism, and Disordered Eating." Eating and Weight Disorders 9 (June 2004): 99-106.
Klentrou, P., and M. Plyley. "Onset of Puberty, Menstrual Frequency, and Body Fat in Elite Rhythmic Gymnasts Compared with Normal Controls." British Journal of Sports Medicine 37 (December 2003): 490-494.
Milsom, S. R., M. C. Sowter, M. A. Carter, et al. "LH Levels in Women with Polycystic Ovarian Syndrome: Have Modern Assays Made Them Irrelevant?" BJOG 110 (August 2003): 760-764.
Nelson, Lawrence M., MD, Vladimir Bakalov, MD, and Carmen Pastor, MD. "Amenorrhea." eMedicine August 9, 2004. http://www.emedicine.com/med/topic117.htm.
Suliman, A. M., T. P. Smith, J. Gibney, and T. J. McKenna. "Frequent Misdiagnosis and Mismanagement of Hyperprolactinemic Patients Before the Introduction of Macroprolactin Screening: Application of a New Strict Laboratory Definition of Macroprolactinemia." Clinical Chemistry 49 (September 2003): 1504-1509.
Webber, L. J., S. Stubbs, J. Stark, et al. "Formation and Early Development of Follicles in the Polycystic Ovary." Lancet 362 (September 27, 2003): 1017-1021.


American Academy of Child and Adolescent Psychiatry. 3615 Wisconsin Avenue, NW, Washington, DC 20016-3007. (202) 966-7300. Fax: (202) 966-2891. http://www.aacap.org.
American College of Sports Medicine (ACSM). 401 West Michigan Street, Indianapolis, IN 46202-3233. (317) 637-9200. Fax: (317) 634-7817. http://www.acsm.org.
Polycystic Ovarian Syndrome Association. P.O. Box 80517, Portland, OR 7280. (877) 775-7267. http://www.pcosupport.org.


Clinical Research Bulletin. vol. 1, no. 14. 〈http://www.herbsinfo.com〉.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.


scanty or infrequent menstruation.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


(ol'i-gō-men'ō-rē'ă), Do not confuse this word with hypomenorrhea.
Scanty menstruation.
[oligo- + menorrhea]
Farlex Partner Medical Dictionary © Farlex 2012


Gynecology Scant menstruation; less than usual menses; menstrual periodicity of 38 to 90 days
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.


Scanty menstruation.
Synonym(s): oligomenorrhoea.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


Scanty menstruation.
Synonym(s): oligomenorrhoea.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Frequency of different gynecological conditions was primary infertility 91 (39.74%), secondary infertility 61 (26.63%), oligomenorrhea 43 (18.78%) and secondary amenorrhea 34 (14.85%) (Fig.
Forty percent of the female NCAA Division I distance runners reported current clinical MD as determined by self-reported symptomatology, indicating the condition of amenorrhea or oligomenorrhea. This is in accordance with the high end of the range of clinical MD reported in the literature in female runners of 6 to 43% (6-8,16,21,37,39).
Oligomenorrhea and ovulatory dysfunction may thus be early clinical signs of androgen excess.
Women, aged 20 to 39 years with infertility and oligomenorrhea were recruited for this study from infertility clinic at Aziz Medical Centre in Karachi, Pakistan, from 1st August 2015 to 31st July 2016.
In thyrotoxicosis oligomenorrhea or amenorrhea is common and fertility hormone levels are increased but normal ovulatory cycles can also occur.
Women over 40 years of age may experience oligomenorrhea associated with the perimenopause.
Diets low in fat and essential fatty acids are associated with luteal phase deficiency, oligomenorrhea, and preterm delivery [37-39].
Etiology of Oligomenorrhea in Iranian traditional medicine:
As stated, oligomenorrhea is very common in the first few years following menarche, but persistent oligomenorrhea is not normal.
Secondary amenorrhea is the absence of menses for three months in women with previously normal menstruation and for nine months in women with previous oligomenorrhea.
Among the several side reactions related with hyperprolactinaemia, are menstrual disorders such as amenorrhea or oligomenorrhea which have not been adequately evaluated.