oligodendroglioma


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oligodendroglioma

 [ol″ĭ-go-den″dro-gli-o´mah]
a neoplasm derived from and composed of oligodendroglia.

ol·i·go·den·dro·gli·o·ma

(ol'i-gō-den'drō-glī-ō'mă),
A relatively rare, relatively slow-growing glioma derived from oligodendrocytes that occurs most frequently in the cerebrum of adult humans; the neoplasm is grossly homogeneous, fairly well circumscribed, moderately firm, and somewhat gritty in consistency with interstitial calcification sufficiently dense so as to be detected by x-ray imaging of the skull. Microscopically, an oligodendroglioma is characterized by numerous small, round or ovoid, oligodendroglial cells with small, deeply stained nuclei (rarely observed in mitosis), and palely stained, indistinct cytoplasm; the neoplastic cells are rather uniformly distributed in a sparse, fibrillary stroma with scattered calcific bodies and an often prominent arcuate vasculature; chemoresponsiveness is associated with loss of heterozygosity on chromosome 1p and 19q.
[oligo- + G. dendron, tree, + glia, + -oma]

oligodendroglioma

/ol·i·go·den·dro·gli·o·ma/ (-den″dro-gli-o´mah) a neoplasm derived from and composed of oligodendrocytes in varying stages of differentiation.

oligodendroglioma

[ol′igōden′drōglī·ō′mə] pl. oligodendrogliomas, oligodendrogliomata
Etymology: Gk, oligos + dendron, tree, glia, glue, oma, tumor
an uncommon brain tumor composed of nonneural ectodermal cells that form part of the supporting connective tissue around nerve cells. The lesion, a firm reddish-gray mass with calcified spots and a distinct margin, may be large. The tumor develops most often in frontal, parietal, and paraventricular sites but also may occur in the cerebellum. Also called oligodendroblastoma.

ol·i·go·den·dro·gli·o·ma

(ol'i-gō-den'drō-glī-ō'mă)
A rare, slowly growing glioma derived from oligodendrocytes that occurs most frequently in the cerebrum of adults.
[oligo- + G. dendron, tree, + glia, + -oma]

oligodendroglioma

A slowly growing tumour of the nervous system derived from neural connective tissue cells, the oligodendroglial cells. The cells of the tumour are small, well-defined ‘halo cells’ with round nuclei and clear CYTOPLASM.

oligodendroglioma, (ol´igōden´drōglēō´mə),

n a relatively rare, moderately well-differentiated, relatively slow-growing glioma that occurs most frequently in the cerebrum of adults. It is grossly homogeneous, fairly well-circumscribed, moderately firm, and somewhat gritty in consistency, with interstitial calcification sufficiently dense to allow detection by radiographic imaging of the skull.

oligodendroglioma

a neoplasm derived from and composed of oligodendroglia.
References in periodicals archive ?
25,26) As a second example, the distinct entity of glioblastoma with oligodendroglioma component" found within the 2007 edition of the WHO (27) has also fallen by the wayside.
CT scan finding of large cystic lesion may be of variable etiology like brain abscess, hydatid cyst, brain infarction, and tumors with central necrosis like oligodendrogliomas, tuberculomas, and many more.
Estimated hazard rates were significantly lower for anaplastic oligodendrogliomas in Quebec (p < 0.
Previous funding through our Oligodendroglioma Research Fund has thankfully provided some much-needed knowledge about how these under-studied tumors develop and progress, as well as a number of potential treatment targets for precision therapeutics," said Carrie Treadwell, chief research officer, National Brain Tumor Society.
Long-term efficacy of early versus delayed radiotherapy for low-grade astrocytoma and oligodendroglioma in adults: the EORTC 22845 randomised trial.
Malignant gliomas include WHO grade III: anaplastic astrocytoma, anaplastic oligodendroglioma and anaplastic oligoastrocytoma, and WHO grade IV: glioblastoma and gliosarcoma.
S1-1: Primary cerebellar extramedullary myeloid cell tumor mimicking oligodendroglioma.
Shamsie's chosen charity, Astrofund is dedicated to finding a cure for low-grade astrocytoma, oligodendroglioma, oligoastrocytoma and ependymoma brain tumours by raising money to support low-grade glioma research projects at neuro-oncology research centres in the UK.
Tumor histology of pediatric patients with brain tumors (n=136) Tumor N Pilocytic astrocytoma (WHO grade I) 42 Medulloblastoma 12 Ependymoma (WHO grades I , II, III) 11 Astrocytoma (WHO grade II) 11 Craniopharyngioma 11 Astrocytoma (WHO (grades III & IV) 6 Choroid plexus papilloma (WHO grade I) 5 Germinoma 5 PNET 5 Dermoid cyst 4 SEGA (WHO grade I) 4 Meningioma 3 Ganglioglioma (WHO grade I) 2 Metastatic 2 Oligodendroglioma (WHO grade II) 3 Choroid plexus carcinoma (WHO grade III) 1 Epidermoid cyst 1 Hemangiopericytoma 1 Pilomyxoid astrocytoma 1 Pineocytoma (WHO grade II) 1 Pleomorphic xanthoastrocytoma 2 Rathke's cleft cyst 1 Schwannoma (WHO grade I) 1 Pituitary adenoma 1 Table 3.
In their lab study, the University of California, San Francisco (UCSF) team found that the pool of cells from which oligodendroglioma tumors emerge normally divide "asymmetrically" by splitting into two unequal parts - like giving birth to fraternal twins who look different and have distinct fates.
His willingness to embrace the ride, no matter how tumultuous, served him well when he was diagnosed at the age of 29 in 1993 with a brain tumor, known as oligodendroglioma.
During the first operation, part of the tumour was removed and Paul was told it was a grade 2 oligodendroglioma.