oligodendroglia

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Related to oligodendroglial: Schwann cells, Oligodendroglial cell

oligodendroglia

 [ol″ĭ-go-den-drog´le-ah]
1. the non-neural cells of ectodermal origin forming part of the adventitial structure of the central nervous system.
2. the tissue composed of such cells.

ol·i·go·den·drog·li·a

(ol'i-gō-den-drog'lē-ă), This word is grammatically singular. Avoid the mispronunciation oligodendrogli'a.
One of the four types of glia cells (the other three being macroglia or astrocytes, ependymal cells, and microglia) that, together with nerve cells, compose the tissue of the central nervous system. Oligodendroglia cells are characterized by variable numbers of veillike or sheetlike processes that are each wrapped around individual axons to form the myelin sheath of nerve fibers in the central nervous system (compared with Schwann cells in the peripheral nervous system); forms myelin in the central nervous system, and accordingly are more numerous in white matter than in gray matter.
Synonym(s): oligodendria
[oligo- + G. dendron, tree, + glia, glue]

oligodendroglia

/ol·i·go·den·drog·lia/ (-den-drog´le-ah)
1. the nonneural cells of ectodermal origin forming part of the adventitial structure (neuroglia) of the central nervous system.
2. the tissue composed of such cells.

oligodendroglia

(ŏl′ĭ-gō-dĕn-drŏg′lē-ə, ō′lĭ-)
n.
Neuroglia consisting of cells similar to but smaller than astrocytes, found in the central nervous system and associated with the formation of myelin.

oligodendroglia

[ol′igōdendrog′lē·ə]
one of three types of glia cells that, with the nerve cells, compose the central nervous system and are characterized by sheetlike processes that wrap around individual axons to form a myelin sheath of nerve fibers.

ol·i·go·den·drog·li·a

(ol'i-gō-den-drog'lē-ă)
One of three types of glia cells (the other two being macroglia or astrocytes, and microglia) that, together with nerve cells, compose the tissue of the central nervous system. Oligodendroglia cells are characterized by variable numbers of veillike or sheetlike processes that are wrapped each around individual axons to form the myelin sheath of nerve fibers in the central nervous system.
Synonym(s): oligodendria.
[oligo- + G. dendron, tree, + glia, glue]

oligodendroglia

1. the non-neural cells of ectodermal origin forming part of the adventitial structure of the central nervous system.
2. the tissue composed of such cells.
References in periodicals archive ?
The prognostic impact of histology and 1p/19q status in anaplastic oligodendroglial tumors.
Loss of the short arm of chromosome 1 (1p), along with the long arm of chromosome 19 (19q), is an established genetic marker of oligodendroglial tumors.
Clear cell ependymoma is a variant of ependymoma that can resemble oligodendroglial differentiation because of the cytoplasmic clearing that is found around the neoplastic cells that may lack ependymal architectural features (Figure 6, A and B).
GRNOPC1 is an allogeneic population of cells containing oligodendroglial progenitors that is intended for transplantation into the lesion site of patients with spinal cord injury to induce tissue repair.
These include small cell astrocytomas (SCAs), glioblastoma with oligodendroglial features (GBM-O), and GBM with primitive neuronal (primitive neuroectodermal tumor [PNET]-like) features.
Reverse transcriptase polymerase chain reaction assays for 1p and 19q performed at our institution have not detected major codeletions of the sort observed in oligodendroglial tumors.
27,28,32) In fact, epidermal growth factor receptor amplification and 10q deletions are sufficiently rare in oligodendroglial tumors that they should prompt the consideration of alternate diagnoses, such as small cell glioblastoma, an astrocytoma variant with features that significantly overlap with those of anaplastic oligodendroglioma.
12) However, only a small fraction of oligodendroglial neoplasms has been found to carry the p18INK4C gene alteration.
Geron Corporation (Nasdaq: GERN) today reported that studies show GRNOPC1, the company's human embryonic stem cell (hESC)-based oligodendroglial progenitor therapeutic, produces multiple nerve growth factors, proteins that stimulate the survival and regeneration of neurons damaged during spinal cord injury.
Ninety-one adult patients with newly diagnosed "pure" cerebral oligodendroglial tumors, consecutively treated at the Neurosurgical Burdenko Institute (Moscow, Russia) between January 1, 1990, and January 1, 1998, were studied retrospectively.